Summary
The polymorphism of DIA3 was investigated in tissues of various human organs, dental pulps, and hair roots by isoelectric focusing. DIA3 types were demonstrated from tissues of brain, prostate, testis, ovary, and uterus, but not from tissues of spleen, pancreas, heart, liver, muscle, lung, skin, and kidney. Determination was possible from dental pulps stored at room temperature for up to 2 weeks and from fresh hair roots. The results show that the DIA3 typing by isoelectric focusing is useful for medicolegal individualization of brain, reproductive organs, teeth, and hairs.
Zusammenfassung
Mittels Isoelektrofokussierung wurden die DIA3-Typen an verschiedenen menschlichen Organgeweben, Zahnpulpen und Haarwurzeln untersucht. Die DIA3-Typen wurden aus Geweben von Gehirn, Prostata, Hoden, Ovarium und Uterus nachgewiesen, aber aus Geweben von Milz, Pankreas, Herz, Leber, Muskel, Lunge, Haut und Niere nicht. Die DIA3-Bestimmung gelang an bis zu 2 Wochen bei Zimmertemperatur gelagerten Zahnpulpen und an frischen Haarwurzeln. Die Ergebnisse zeigen, daß die DIA3-Typisierung mittels Isoelektrofokussierung zur rechtsmedizinischen Individualisierung von Gehirn, Geschlechtsorganen, Zähnen und Haaren von Nutzen ist.
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Kido, A., Komatsu, N., Oya, M. et al. DIA3 phenotyping in human tissues, dental pulps, and hair roots by isoelectric focusing. Z Rechtsmed 100, 133–137 (1988). https://doi.org/10.1007/BF00200753
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DOI: https://doi.org/10.1007/BF00200753
Key words
- Isoelectric focusing, DIA3 polymorphism
- DIA3 phenotyping, in organ tissues
- DIA3 phenotyping, in dental pulps
- DIA3 phenotyping, in hair roots