Summary
The distribution of plasminogen phenotypes in the population of Veneto was investigated by ultrathin-layer isoelectric focusing. In our sample (n=1325), the three common phenotypes PLG1, PLG2, PLG2-1 and two further phenotypes PLG1-V and PLG2-V were, observed and the following frequencies calculated: PLG1=0.84038; PLG2=0.15811; PLGV=0.00151. These gene frequencies are compared to those found in other populations. Analysis of 41 mother-child pairs was in agreement with an autosomal codominant inheritance.
Zusammenfassung
Die Verteilung der PLG-Phänotypen wurde bei der venetischen Bevölkerung mittels Isoelektrofokussierung untersucht. In unseren Stichproben wurde die PLG-Phänotypen PLG1, PLG2, PLG2-1 und zwei weitere Phänotypen PLG1-V und PLG2-V beobachtet und folgende Frequenzen berechnet: PLG1=0.84038; PLG2=0.15811; PLGV=0.00151. Diese Genfrequenzen wurde mit den bei anderen Bevölkerungsgruppen gefundenen Frequenzen verglichen. Die Untersuchung von 41 Mutter-Kind-Paaren zeigte eine autosomal-kodominante Relation.
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Financially supported by the Ministry of Education of Italy
The results were partially communicated at the 11th International Congress of the Society of Forensic Hemogenetics, Copenhagen 1985
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Cortivo, P., Caenazzo, L., Crestani, C. et al. The polymorphism of plasminogen (PLG) by ultrathin-layer isoelectric focusing. Z Rechtsmed 96, 275–278 (1986). https://doi.org/10.1007/BF00200706
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DOI: https://doi.org/10.1007/BF00200706