Skip to main content

Anti-cholinesterase action of a new organophosphorus ester, diethylphosphoric ester of the dicyclopropyloketoxime, on wistar rats

This is a preview of subscription content, access via your institution.


  1. Ellman GL, Courtney KD, Anders V, Featherstone RM (1961) A new rapid colorimetric determination of acetyl-cholinesterase activity. Biochem Pharmacol 7: 88–95.

    Article  CAS  PubMed  Google Scholar 

  2. Frawley JP, Hagan EC, Fitzhugh OG (1952) A comparative pharmacological and toxicological study of organic phosphate anticholinesterase compounds. J Pharmac Exp Ther 105: 156–165.

    Google Scholar 

  3. Heath DF (1961) Organophosphorus poissons. Pergamon Press, Oxford.

    Google Scholar 

  4. Machera K (1990) Toxicological study of the new organophosphorus insecticide diethylphosphoric ester of the dicyclopropyloketoxime. Ph.D. Thesis, Univ. of Athens.

  5. Machera K, Kostakis E (1991) Acute toxicity of the organophosphorus compound diethylphosphoric ester of the dicyclopropyloketoxime and efficacy of antitodes on white rats. Annls Inst Phytopath Benaki (N.S.) (in press).

  6. Michailides S (1986) Studies on the stability and residues of the new insecticide “Diethylphosphoric ester of the dicyclopropyloketoxime” Ph.D. Thesis, Univ. of Athens.

  7. O'Brien RD (1960) Toxic phosphorus esters. Chemistry metabolism and biological effects. Academic Press, New York.

    Google Scholar 

  8. Rouman AA (1984) Synthesis and pharmacological study of new anticolinergic compounds. Ph.D. Thesis, Univ. of Athens.

  9. Smith LH, Odell TT, Caldwell B (1959) Life spann of rat erythrocytes as determined by Cr51 and differential agglutination method. Proc Soc Exptl Biol and Med 100(1): 29–31.

    Google Scholar 

  10. Sawyer CH, Everett JW (1946) Effects of various hormonal conditions in the intact rat on the synthesis of serum cholinesterase. Endocrinology 30: 307–322.

    Google Scholar 

  11. Vandekar M (1980) Minimizing occupational exposure to pesticides: Cholinesterase determination and organophosphorus poisoning. Res Rev 75: 67–80.

    Google Scholar 

  12. Voss G, Sachsee K (1970) Red cell and plasma cholinesterase activities in microsamples of human and animal blood determined simultaneously by a modified acetylthiocholine/DTNB procedure. Toxicol Appl Pharmacol 16: 764–772.

    Google Scholar 

Download references

Author information



Corresponding author

Correspondence to K. Machera.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Machera, K., Kostakis, E. Anti-cholinesterase action of a new organophosphorus ester, diethylphosphoric ester of the dicyclopropyloketoxime, on wistar rats. Bull. Environ. Contam. Toxicol. 48, 108–114 (1992).

Download citation


  • Ester
  • Waste Water
  • Water Management
  • Water Pollution
  • Organophosphorus Ester