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Autoimmune Addison's disease

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References

  1. Ahonen P, Meittenen A, Perheentupa J (1987) Adrenal and steroidal cell antibodies in patients with autoimmune polyglandular disease type I and risk of adrenocortical and ovarian failure. J Clin Endocrinol Metab 64:494

    Google Scholar 

  2. Anderson JR, Goudie RB, Gray KG, Timbury GC (1957) Autoantibodies in Addison's disease. Lancet I:1123

    Google Scholar 

  3. Anderson JU, Goudie RB, Gray K et al. (1968) Immunological features of idiopathic Addison's disease: an antibody to cells producing steroid hormones. Clin Exp Immunol 3:107

    Google Scholar 

  4. Andrada JA, Bigazzi PE, Andrada EC, Milgrom F, Witebsky E (1968) Serological investigations on Addison's disease. JAMA 206:1535

    Google Scholar 

  5. Asherson RA, Hughes GRV (1991) Hypoadrenalism, Addison's disease and antiphospholipid antibodies. J Rheumatol 18:1

    Google Scholar 

  6. Baumann-Antczak A, Wedlock N, Bednarek J et al. (1992) Autoimmune Addison's disease and 21-hydroxylase. Lancet 340:429

    Google Scholar 

  7. Betterle C, Zanchetta R, Trevisan A, Zanette F, Pedini B, Mantero F, Rigon F (1983) Complement-fixing adrenal autoantibodies as a marker for predicting onset of idiopathic Addison's disease. Lancet I:1238

    Google Scholar 

  8. Betterle C, Scalici C, Presotto F, Pedini B, Moro L, Rigon F, Mantero F (1988) The natural history of adrenal function in autoimmune patients with adrenal autoantibodies. J Endocrinol 117:467

    Google Scholar 

  9. Betterle C, Scalici C, Pedini B, Mantero F (1989) Addison's disease: principal clinical associations and description of natural history of the disease. Ann Ital Med Intern 4:195–206

    Google Scholar 

  10. Bigazzi PE (1986) Autoimmunity of the adrenals. In: Volpe R (ed) Autoimmunity and endocrine disease. Marcel Dekker, New York, pp 345–373

    Google Scholar 

  11. Bigazzi PE (1990) Autoimmune Addison's disease. In: Volpe R (ed) Autoimmune diseases of the endocrine system. CRC Press, Boca Raton, pp 297–330

    Google Scholar 

  12. Boehm BO, Manfras B, Siedl S, Holzberger G, Kühnl P, Rosak C, Schöffling K, Trucco M (1991) The HLA-DQβ non-Asp-57 allele: a predictor of future insulin-dependent diabetes mellitus in patients with autoimmune Addison's disease. Tissue Antigens 37:130

    Google Scholar 

  13. Bona CA (1991) Postulates defining pathogenic autoantibodies and T cells. Autoimmunity 10:169

    Google Scholar 

  14. Bright GM, Singh I (1990) Adrenal autoantibodies bind to adrenal subcellular fractions enriched in cytochtome c reductase and 5′-nucleotidase. J Clin Endocrinol Metab 70:95

    Google Scholar 

  15. Eason RJ, Croxson MS, Perry MC, Somerfield SD (1982) Addison's disease, adrenal autoantibodies and computerised adrenal tomography. NZ Med J 95:569

    Google Scholar 

  16. Elder M, Maclaren N, Riley W (1981) Gonadal autoantibodies in patients with hypogonadism and/or Addison's disease. J Clin Endocrinol Metab 52:1137

    Google Scholar 

  17. Fairchild RS, Schimke RN, Abdou NI (1980) Immunoregulation abnormalities in familial Addison's disease. J Clin Endocrinol Metab 51:1074

    Google Scholar 

  18. Furmaniak J, Talbot D, Reinwein D, Benker G, Creagh FM, Rees Smith B (1988) Immunoprecipitation of human adrenal microsomal antigen. FEBS Lett 231:25

    Google Scholar 

  19. Garcia PL, Simo CR, Mesa MJ, Obiols AG, Segura GA, Gonzalez AJ (1990) Addison's disease: a clinico-epidemiologic study of 45 cases. Rev Clin Esp 187:49

    Google Scholar 

  20. Harris EN (1990) Antiphospholipid antibodies. Br J Haematol 74:1

    Google Scholar 

  21. Hayashi Y, Hiyoshi T, Takemura T, Kurashima C, Hirokawa K (1989) Focal lymphocytic infiltration in the adrenal cortex of the elderly: immunohistological analysis of infiltrating lymphocytes. Clin Exp Immunol 77:101

    Google Scholar 

  22. Irvine WJ, Barnes EW (1972) Adrenocortical insufficiency. Clin Endocrinol Metab 1:549

    Google Scholar 

  23. Jackson R, McNicol AM, Farquharson M, Foulis AK (1988) Class II MHC expression in normal adrenal cortex and cortical cells in autoimmune Addison's disease. J Pathol 155:113

    Google Scholar 

  24. Kendall-Taylor P, Lambert A, Mitchell R, Robertson WR (1988) Antibody that blocks stimulation of cortisol secretion by adrenocorticotrophic hormone in Addison's disease. Br Med J 296:1489

    Google Scholar 

  25. Ketchum CH, Riley WJ, Maclaren NK (1984) Adrenal dysfunction in asymptomatic patients with adrenocortical autoantibodies. J Clin Endocrinol Metab 58:1166

    Google Scholar 

  26. Khoury EL, Hammond L, Bottazzo GF, Doniach D (1981) Surface-reactive antibodies to human adrenal cells in Addison's disease. Clin Exp Immunol 45:48

    Google Scholar 

  27. Khoury EL, Greenspan JS, Greenspan FS (1987) Androcortical cells of the zona reticularis normally express HLA-DR antigenic determinants. Am J Pathol 127:580

    Google Scholar 

  28. Krohn K, Uibo R, Aarik E, Peterson P, Savilahti K (1992) Identification by molecular cloning of an autoantigen associated with Addison's disease as 17α-hydroxylase. Lancet 339:770

    Google Scholar 

  29. Latinne D, Vandeput Y, De Bruyere M, Bottazzo F, Sokal G, Crabbe J (1987) Addison's disease: immunological aspects. Tissue Antigens 30:23

    Google Scholar 

  30. Ludwig H, Schernthaner G (1978) Multiorganspezifische Autoimmunität bei idiopathischer Nebennierenrindeninsuffizienz. Wein Klin Wochenschr 90:736

    Google Scholar 

  31. Maclaren NK, Riley WJ (1986) Inherited susceptibility to autoimmune Addison's disease is linked to human leukocyte antigens-DR3 and/or DR4, except when associated with type I polyglandular syndrome. J Clin Endocrinol Metab 62:455

    Google Scholar 

  32. Mason AS, Meade TW, Lee JAH et al. (1968) Epidemiological and clinical picture of Addison's disease. Lancet II:744

    Google Scholar 

  33. Nerup J (1974) Addison's disease — clinical studies: a report of 108 cases. Acta Endocrinol (Copenh) 76:127

    Google Scholar 

  34. Nerup J, Bendixen G (1969) Anti-adrenal cellular hypersensitivity in Addison's disease. 2. Correlation with clinical and serological findings. Clin Exp Immunol 5:341

    Google Scholar 

  35. Nerup J, Bendixen G (1969) Anti-adrenal cellular hypersensitivity in Addison's disease. 3. Species specificity and subcellular localization of the antigen. Clin Exp Immunol 5:355

    Google Scholar 

  36. Petri M, Nerup J (1971) Addison's adrenalitis. Studies on diffuse lymphocytic adrenalitis (idiopathic Addison's disease) and focal lymphocytic infiltration in a control material. Acta Pathol Microbiol Scand 79:381

    Google Scholar 

  37. Rabinowe SL, Jackson RA, Dluhy RG, Williams GH (1984) Ia-positive T lymphocytes in recently diagnosed idiopathic Addison's disease. Am J Med 77:597

    Google Scholar 

  38. Salim YS, Faver V, Wiik A, Andersen PL, Høier-Madsen M, Mouritsen S (1988) Anti-corticosteroid antibodies in AIDS patients. APMIS 96:889

    Google Scholar 

  39. Scherbaum WA, Berg PA (1982) Development of adrenocortical failure in non-Addisonian patients with antibodies to adrenal cortex. Clin Endocrinol (Oxf) 16:345

    Google Scholar 

  40. Sloper JC (1955) The pathology of the adrenals, thymus and certain other endocrine glands in Addison's disease: an analysis of 37 micropsies. Proc R Soc Med 48:625

    Google Scholar 

  41. Stechmesser E, Scherbaum WA, Grassmann T, Berg BA (1985) An ELISA method for detection of autoantibodies to adrenal cortex. J Immunol Methods 80:67

    Google Scholar 

  42. Verghese MW, Ward FE, Eisenbarth GS (1980) Decreased suppressor cell activity in patients with polyglandular failure. Clin Res 28:270A

    Google Scholar 

  43. Volpe R (1978) The role of autoimmunity in hypoendocrine and hyperendocrine function. Ann Intern Med 87:86

    Google Scholar 

  44. Winqvist O, Karlsson FA, Kämpe O (1992) 21-hydroxylase, a major autoantigen in idiopathic Addison's disease. Lancet 339:1559

    Google Scholar 

  45. Wulffraat NM, Drexhage HA, Bottazzo G-F, Wiersinga WM, Jeucken P, Van der Gaag R (1989) Immunoglobulins of patients with idiopathic Addison's disease block the in vitro action of adrenocorticotropin. J Clin Endocrinol Metab 69:231

    Google Scholar 

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Authors and Affiliations

  1. Department of Pathology and Laboratory Medicine, J. H. Miller Health Center, University of Florida College of Medicine, Box J-275, 32610, Gainesville, FL, USA

    Andrew Muir, Desmond A. Schatz & Noel K. Maclaren

  2. Department of Pediatrics, J. H. Miller Health Center, University of Florida College of Medicine, Box J-275, 32610, Gainesville, FL, USA

    Andrew Muir, Desmond A. Schatz & Noel K. Maclaren

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  1. Andrew Muir
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  2. Desmond A. Schatz
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Muir, A., Schatz, D.A. & Maclaren, N.K. Autoimmune Addison's disease. Springer Semin Immunopathol 14, 275–284 (1993). https://doi.org/10.1007/BF00195978

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