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Early malignant histiocytosis of the intestine: an autopsy report

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Abstract

A 63-year-old man with malignant histiocytosis of the intestine died 3 days after gastrectomy for early gastric adenocarcinoma. Malignant histiocytosis of the intestine was unexpectedly found at autopsy. The intestine was thickened with mucosal erosions. Histologically, a few atypical large histiocyte-like cells were found in focal aggregates in the mucosa. These large cells expressed the T-cell antigen and monoclonality was demonstrated by the polymerase chain reaction showing variable-joining segment rearrangement in the T-cell receptor delta-chain gene. Malignant histiocytosis of the intestine was thus diagnosed.

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Ohshima, K., Yoshitake, K., Kikuchi, M. et al. Early malignant histiocytosis of the intestine: an autopsy report. Vichows Archiv A Pathol Anat 424, 327–330 (1994). https://doi.org/10.1007/BF00194619

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  • DOI: https://doi.org/10.1007/BF00194619

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