Summary
Thirty-nine recombinants isolated from a Y chromosome-specific library were deletion mapped. Seven deletion intervals were defined by hybridization of probes to DNA of eight individuals with aberrant Y chromosomes. Extreme cytogenetic limits of the deletion intervals were determined by in situ hybridization of one probe per deletion interval. Five intervals, with a total of twenty-five probes, were allocated to the longarm euchromatic region. The probes described will be useful for characterization of aberrant Y chromosomes, in searching for expressed sequences on the Y chromosome, and for further study of the evolutionary relationship between the Y chromosome and other chromosomes.
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Oosthuizen, C.J.J., Herbert, J.S., Vermaak, L.K. et al. Deletion mapping of 39 random isolated Y-chromosome DNA fragments. Hum Genet 85, 205–210 (1990). https://doi.org/10.1007/BF00193197
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DOI: https://doi.org/10.1007/BF00193197