Abstract
Four patients with symptomatic Paget's disease of the appendicular skeleton were evaluated by magnetic resonance (MR) imaging. The plain film findings in each case were advanced but dissimilar. All patients had progressive symptoms of pain, and one presented with excruciating pain of short duration. The radiographic features included diffuse progressive osteolysis, cortical resorption, insufficiency fractures, bowing, and cortical and trabecular thickening. In three of the patients, MRI was performed to exclude sarcoma, revealing preservation of fatty marrow signal in all phases of Paget's disease except in patients with an acute fracture (demonstrated by MRI) and sarcoma. Small, focal, linear or oval areas of low signal seen against a background of normal marrow signal on short or long TR/ TE do not mimic tumor. These findings suggest that fatty marrow signal is preserved in advanced Paget's disease unless an acute fracture or tumor is present.
Similar content being viewed by others
References
Greditzer HG III, McLeod RA, Unni KK, Beabout JW (1983) Bone sarcomas in Paget's disease. Radiology 146:327
Joplin GF, Stevenson JC (1990) Paget's disease of bone. In: Stevenson JC (ed) New techniques in metabolic bone disease. Wright, Boston, p 266
Resnick D (1988) Paget disease of bone: current status and a look back to 1943 and earlier. AJR 150:249
Revell PA (1985) Paget's disease. In: Revell PA (ed) Pathology of bone. Springer, Berlin Heidelberg New York, p 147
Roberts MC, Kressel HY, Fallon MD, Zlatkin MB, Dalinka MK (1989) Paget disease: MR imaging findings. Radiology 173:341
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Kaufmann, G.A., Sundaram, M. & McDonald, D.J. Magnetic resonance imaging in symptomatic Paget's disease. Skeletal Radiol. 20, 413–418 (1991). https://doi.org/10.1007/BF00191082
Issue Date:
DOI: https://doi.org/10.1007/BF00191082