Structure and polymorphism of horse MHC class II DRB genes: convergent evolution in the antigen binding site

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References

  1. Andersson, G., Larhammar, D., Widmark, E., Servenius, B., Peterson, P. A., and Rask, L. Class II genes of the human major histocompatibility complex: organization and evolutionary relationship of the DRß genes. J Biol Chem 262: 8748–8758, 1987

    Google Scholar 

  2. Andersson, L., Sigurdardottir, S., Borsch, C., and Gustafsson, K. Evolution of MHC polymorphism: extensive sharing of polymorphic sequence motifs between human and bovine DRB alleles. Immunogenetics 33: 188–193, 1991

    Google Scholar 

  3. Bell, J. I., Estess, P., St. John, Saiki, R., Watling, D. L., Ehrlich, H. A., and McDevitt, H. O. DNA sequence and characterization of human class II major histocompatibility complex \gB chains from the DR1 haplotype. Proc Natl Acad Sci USA 82: 3405–3409, 1985

    Google Scholar 

  4. Bell, J. I., Denney, D. J., Foster, L., Belt, T., Todd, J. A., and McDevitt, H. O. Allelic variation in the DR subregion of the human major histocompatibility complex. Proc Natl Acad Sci USA 84: 6234–6238, 1987

    Google Scholar 

  5. Denaro, M., Hammerling, U., Rask, L., and Peterson, P. A. The Ebß gene may have acted as the donor gene in a gene conversion-like event generating the Abm12ß mutant. EMBO J 7: 3745–3753, 1984

    Google Scholar 

  6. Gustafsson, K., Wiman, K., Emmoth, E., Larhammar, D., Böhme, J., Hyldig-Nielsen, J. J., Ronne, H., Peterson, P. A., and Rask, L. Mutations and selection in the generation of class II histocompatibility antigen polymorphism. EMBO J 3: 1655–1661, 1984

    Google Scholar 

  7. Gustafsson, K., Germana, S., Hirsch, F., Pratt, K., LeGuern, C., and Sachs, D. H. Structure of miniature swine class II DRB genes: conservation of hypervariable amino acid residues between distantly related species. Proc Natl Acad Sci USA 87: 9798–9802, 1990

    Google Scholar 

  8. Lundberg, A. S. and McDevitt, H. O. Evolution of major histocompatibility complex class II diversity: direct descent in mice and humans. Proc Natl Acad Sci USA 89: 6545–6549, 1992

    Google Scholar 

  9. Marsh, S. G. E. and Bodmer, J. G. HLA class II nucleotide sequences, 1992. Eur J Immunogenetics 20: 47–79, 1993

    Google Scholar 

  10. Mengle-Gaw, L. and McDevitt, H. O. Predicted protein sequence of the murine I-EßS polypeptide chain from cDNA and genomic clones. Proc Natl Acad Sci USA 82: 2910–2914, 1983

    Google Scholar 

  11. Robertson, K. A. and McMaster, W. R. Complete structure of a rat RT1 Eß chain: extensive conservation of MHC class II \gB chains. J Immunol 135: 4095–4099, 1985

    Google Scholar 

  12. Sarmiento, U. M., Sarmiento, J. I., and Storb, R. Allelic variation in the DR subregion of the canine major histocompatibility complex. Immunogenetics 32: 13–19, 1990

    Google Scholar 

  13. Sigurdardottir, S., Borsch, C., Gustafsson, K., and Andersson, L. Cloning and sequence analysis of 14 DRB1 alleles of the bovine MHC by using the polymerase chain reaction. Anim Genet 22: 199–209, 1991

    Google Scholar 

  14. Spies, T., Sorrentino, R., Boss, J. M., Okada, K., and Strominger, J. L. Structural organization of the DR subregion of the human major histocompatibility complex. Proc Natl Acad Sci USA 82: 5165–5169, 1985

    Google Scholar 

  15. Tonnelle, C., DeMars, R., and Long, E. O. DOß: a new β chain gene in HLA-D with a distinct regulation of expression. EMBO J 4: 2839–2847, 1985

    Google Scholar 

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Correspondence to Kenth Gustafsson.

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The nucleotide sequence data reported in this paper have been submitted to the GenBank nucleotide sequence database and have been assigned the accession numbers L25644-25646.

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Gustafsson, K., Andersson, L. Structure and polymorphism of horse MHC class II DRB genes: convergent evolution in the antigen binding site. Immunogenetics 39, 355–358 (1994). https://doi.org/10.1007/BF00189233

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Keywords

  • Binding Site
  • Convergent Evolution
  • Antigen Binding
  • Antigen Binding Site