References
Bendtzen, K., Morling, N., Fomsgaard, A., Svenson, M., Jakobsen, B., Odum, N., and Svejgaard, A. Association between HLA-DR2 and production of tumor necrosis factor α and interleukin 1 by mononuclear cells activated by lipopolysaccharide. Scand J Immunol 28: 599–606, 1988
Benoist, C. and Mathis, D. Regulation of major histocompatibility complex class-II genes: X, Y and other letters of the alphabet. Annu Rev Immunol 8: 681–715, 1990
Beutler, B. and Cerami, A. The biology of cachectin/TNF — a primary mediator of the host response. Annu Rev Immunol 7: 625–655, 1989
Bidwell, J. DNA-RFLP analysis and genotyping of HLA-DR and DQ antigens. Immunology Today 9: 18–23, 1988
Browning, J. L., Ngam-ek, A., Lawton, P., Tizard, R., Chow, E. P., Hession, C., O'Brine-Greco, B., Foley, S. F., and Ware, C. F. Lymphotoxin β, a novel member of the TNF family that forms a heteromeric complex with lymphotoxin on the cell surface. Cell 72: 847–856, 1993
Calladine, C. R., Drew, H. R., and McCall, M. J. The intrinsic curvature of DNA in solution. J Mol Biol 201: 127–137, 1988
Cascino, I., Sorrentino, R., and Tosi, R. Strong genetic association between HLA-DR3 and a polymorphic variation in the regulatory region of the HSP70–1 gene. Immunogenetics 37: 177–182, 1993a
Cascino, I., D'Alfonso, S., Cappello, N., Giordano, M., Pugliese, A., Awdeh, Z., Alper, C. A., and Momigliano Richiardi, P. Gametic association of HSP70–1 promoter region alleles and their inclusion in extended HLA haplotypes. Tissue Antigens 42: 62–66, 1993b
D'Alfonso, S., Cappello, N., Borelli, I., Mazzola, G., Peruccio, D., Giordano, M., Cascino, I., Tosi, R., and Momigliano Richiardi, P. HLA supratypes in an Italian population. Immunogenetics: in press
Degli-Esposti, M. A., Leaver, A. L., Christiansen, F. T., Witt, C. S., Abraham, L. J., and Dawkins, R. L. Ancestral haplotypes: conserved population MHC haplotypes. Hum Immunol 34: 242–252, 1992
De Santis, P., Palleschi, A., Savino, M., and Scipioni, A. A theoretical model of DNA curvature. Biophys Chem 32: 305–317, 1988
Drouet, C., Shakhov, A. N., and Jongeneel, C. V. Enhancers and transcription factors controlling the inducibility of the tumor necrosis factor-α promoter in primary macrophages. J Immunol 147: 1694–1700, 1991
Economou, J. S., Rhoades, K., Essner, R., McBride, W. H. Gasson, J. C., and Morton, D. L. Genetic analysis of the human tumor necrosis factor α cachectin promoter region in a macrophage cell line. J Exp Med 170: 321–326, 1990
Golfeld, A. E., Doyle, C., and Maniatis, T. Human tumor necrosis factor α gene regulation by virus and lipopolysaccharide. Proc Natl Acad Sci USA 87: 9769–9773, 1990
Golfeld, A. E., Strominger, J. L., and Doyle, C. Human tumor necrosis factor α gene regulation in phorbol ester stimulated T and B cell lines. J Exp Med 174: 73–81, 1991
Haas, J. P., Kimura, A., Sasazuki, T., Schoenwald, U., Hoza, J., Suschke, J., Volgger, A., and Albert, E. DQA1 upstream regulatory region: polymorphism of the Y-box in early onset pauciarticular JCA. Human Immunol 36: 47–47, 1993
Han, J., Brown, T., and Beutler, B. Endotoxin-responsive sequences control cachectin/tumor necrosis factor biosynthesis at the translational level. J Exp Med 171: 465–475, 1990
Han, J., Huez, G., and Beutler, B. Interactive effects of the tumor necrosis factor promoter and 3' 3′-untranslated regions. J Immunol 146: 1843–1848, 1991
Jacob, C. O., Fronek, Z., Lewis, G. D., Koo, M., Hansen, J. A., and McDevitt, H. O. Hereditable major histocompatibility complex class II-associated differences in production of tumor necrosis factor α: relevance to genetic predisposition to systemic lupus erythematosus. Proc Natl Acad Sci USA 87: 1233–1237, 1990
Mattiuz, P. L., Ihde, D., Piazza, A., Ceppellini, R., and Bodmer, W. D. New approaches to the population genetics and segregation analysis of the HLA system. In P. Terasaki (ed.): Histocompatibility Testing, pp 193–205, Munksgaard, Copenhagen, 1970
Messer, G., Spengler, U., Jung, M. C., Honold, G., Blomer, K., Pape, G. R., Riethmuller, G., and Weiss, E. H. Polymorphic structure of the tumor necrosis factor (TNF) locus: an Nco I polymorphism in the first intron of the human TNF-β gene correlates with a variant amino acid in position 26 and a reduced level of TNF-β production. J Exp Med 173: 209–219, 1991
Nedospasov, S. A., Shakhov, A. N., Turetskaya, R. L., Mett, V. A., Azizov, M. M., Georgiev, G. P., Korobko, V. G., Dobrynin, V. N., Filippov, S. A., Bystrov, N. S., Boldyreva, E. F., Chuvpilo, S. A., Chumakov, A. M., Shingarova, L. N., and Ovchinnikov, Y. A. Tandem arrangement of genes coding for tumor necrosis factor (TNF-α) and lymphotoxin (TNF-β) in the human genome. Cold Spring Harbor Symp Quant Biol 51: 611–624, 1986
Nedwin, G. E., Naylor, S. L., Sakagucho, A. J., Smith, D., Jarett-Nedwin, J., Pennica, D., Goeddel, D. V., and Gray, P. W. Human lymphotoxin and tumor necrosis factor genes: structure, homology and chromosomal localization. Nucleic Acids Res 13: 1487–1492, 985
Perez-Martin, J. and Espinosa, M. Protein-induced bending as a transcriptional switch. Science 260: 805–807, 1993
Pociot, F., Briant, L., Jongeneel, C. V., Molvig, J., Worsaae, H., Abbal, M., Thomsen, M., Nerup, J., and Cambon-Thomsen, A. Association of tumor necrosis factor (TNF) and class II major histocompatibility complex alleles with the secretion of TNF-α and TNF-β by human mononuclear cells: a possible link to insulin-dependent diabetes mellitus. Eur J Immunol 23: 224–231, 1993
Shakhov, A. N., Collart, M. A., Vassalli, P., Nedospasov, S. A., and Jongeneel, C. V. kB-type enhancers are involved in lipopolysaccharide-mediated transcriptional activation of the tumor necrosis factor α gene in primary macrophages. J Exp Med 171: 35–47, 1990
Spies, T., Morton, C. C., Nedospasov, S. A., Fiers, W., Pious, D., and Strominger, J. I. Genes for tumour necrosis factor alpha and beta are linked to the major histocompatibility complex. Proc Natl Acad Sci USA 83: 8699–8702, 1986
Sung, S-S. J., Walters, J. A., Hudson, J., and Gimble, J. M. Tumor necrosis factor-α mRNA accumulation in human myelomonocytic cell lines. J Immunol 147: 2047–2054, 1991
Travers, A. A. Why bend DNA? Cell 60: 177–180, 1990
Wilson, A. G., de Vries, N., Pociot, F., di Giovine, F. S., van der Putte, L. B. A., and Duff, G. W. An allelic polymorphism within the human tumor necrosis factor α promoter region is strongly associated with HLA A1, B8, and DR3 alleles. J Exp Med 177: 557–560, 1993
Yang, S. Y., Milford, E., Hämmerling, U., and Dupont, B. Description of the reference panel of B-lymphoblastoid cell lines for factors of the HLA system: the B-cell line panel designed for the Tenth International Histocompatibility Workshop. In B. Dupont (ed.): Immunobiology of HLA Histocompatibility Testing 1987, vol. I, pp. 11–19, Springer, New York Berlin Heidelberg, 1989
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D'Alfonso, S., Richiardi, P.M. A polymorphic variation in a putative regulation box of the TNFA promoter region. Immunogenetics 39, 150–154 (1994). https://doi.org/10.1007/BF00188619
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DOI: https://doi.org/10.1007/BF00188619