Summary
The incidence of multiple primary melanoma is reported as 1–6% of patients with cutaneous melanoma. The patient who already has one melanoma has a greater risk of developing a second primary melanoma than a person who does not have a melanoma. Hence patients with one melanoma require complete skin examinations at regular follow up visits to detect metachronous disease. Dysplastic nevi should also be sought and a family history of melanoma or dysplastic nevi investigated. This report describes a patient who developed four metachronous primary melanomas. Diagnosis, risk factors and management is discussed.
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References
Beardmore GL, Davis NC (1975) Multiple primary cutaneous melanomas. Arch Dermatol 111:603–699
Bellet RE, Vaisman I, Mastrongelo MJ et al (1977) Multiple primary malignancies in patients with cutaneous melanoma. Cancer 40:1974–1981
Cascinelli N, Fontana V, Cataldo I et al (1975) Multiple primary melanoma. Tumori 61:481–486
Kang S, Barnhill RL, Mihm MC et al (1972) Multiple primary cutaneous melanoma. Cancer 70:1911–1916
Koh HK (1991) Cutaneous melanoma. N Engl J Med 325:171–182
Moseley SH, Gruliano AE, Storm FK et al (1979) Multiple primary melanoma. Cancer 43:939–944
Reimer RR, Clark WH, Greene MH et al (1978) Precursor lesions in familial melanoma. J Am Med Assoc 239:744–749
Russell LC, Murray J (1992) Patient education: recommendations regarding sunscreens, drugs and diet. Ann Plast Surg 28:14–16
Scheibner A, Milton GW, McCarthy WH et al (1982) Multiple primary melanoma: a review of 90 cases. Aust J Dermatol 23:1–8
Titus-Ernstoff L, Duray PH, Ernstof MS et al (1988) Dysplastic nevi in association with multiple primary melanoma. Cancer Res 48:1016–1018
Tucker MA, Boice JD, Hoffman DA (1985) Second cancer following cutaneous melanoma and cancers of the brain, thyroid, connective tissue, bone and eye in Connecticut, 1935–1982. NCI Monogr 68:161–189
Veronesi U, Cascinelli N, Bufalino R (1976) Evaluation of the risk of multiple primaries in malignant cutaneous melanoma. Tumori 62:127–130
Wallace DC, Beardmore GL, Exton LA (1971) Familial malignant melanoma. Ann Surg 177:15–20
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Correspondence to: Dr. D.A. Hudson
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Hudson, D.A., Krige, J.E.J. Multiple metachronous cutaneous malignant melanomas. Eur J Plast Surg 17, 202–203 (1994). https://doi.org/10.1007/BF00188564
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DOI: https://doi.org/10.1007/BF00188564