Summary
Tumorgenesis and tumor growth are connected with the immune system. Therefore the role of the spleen respectively splenectomy have gained increasing influence. The existing experimental and clinical results are discussed with the help of a general review of the literature. A manipulation of the immune system by splenectomy seems possible. A common pathomechanism has not yet been found. But experimental investigations are transferrable to human beings only under special conditions.
Zusammenfassung
Tumorgenese und -progredienz stehen in engem Zusammenhang mit dem Immunsystem. zunehmend werden die Rolle der Milz beziehungsweise der Splenektomie diskutiert. Anhand einer Literaturübersicht werden die bisher vorliegenden experimentellen und klinischen Ergebnisse dargelegt. Danach ist eine Beeinflussung des Immunsystems durch Splenektomie möglich. Ein allgemein gültiger Pathomechanismus ist aber noch nicht gefunden. Experimentelle Ergebnisse sind allerdings nur bedingt auf den Menschen übertragbar.
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Wolters, U., Keller, H.W. & Pichlmaier, H. Die rolle der milz in der tumorchirurgie. Langenbecks Arch Chir 376, 280–285 (1991). https://doi.org/10.1007/BF00188268
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DOI: https://doi.org/10.1007/BF00188268