Abstract
In order to determine and to demonstrate the cellular iron molecular states in hematopoietic bone marrow, direct investigations were performed by means of different and complementary spectroscopic techniques: optical absorption, electron spin resonance and Mössbauer spectrometry. In fact, the latter appears to have been the most informative. In addition to the hemoglobin forms, five- and six-coordination ligand protoporphyrins IX (monomeric and polymeric stacking, respectively) were observed. A small amount of non-hemic high-spin iron III storage component (ferritin) was measured. No diferric transferrin was detected. A ferrous compound was also observed and attributed to the mitochondrial iron pool.
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Jumpertz, CM., Rimbert, JN. Identification and characterization of the iron compounds in bone marrow by means of Mössbauer spectrometry. Biometals 6, 207–212 (1993). https://doi.org/10.1007/BF00187757
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DOI: https://doi.org/10.1007/BF00187757