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Lectin-binding patterns in the development of the cerebellum

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Abstract

We studied the binding distribution of several lectins, Con A, DBA, UEA and WGA, in the embryonic development of the chick cerebellum between stages 18 to 45 of Hamburger and Hamilton. We observed a differential labeling (in intensity and distribution) in the migratory and cortical layers of the cerebellum anlage with these different lectins. The different distributions and modifications in the labeling pattern suggest intense variations of the glycoproteins and glycosaminoglycans in the extracellular matrix during development. These variations coincide with cellular and organizational phenomena in the migratory and cortical layers, and suggest compartmentalization of the Purkinje cell labeling.

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Abbreviations

egl:

External granular layer

fv:

fourth ventricle

iccl:

internal cortical cell layer

igl:

internal granular layer

mA:

migratory A layer

mB:

migratory B layer

m2:

migratory A2B layer

ml:

mantle layer

mo:

molecular layer

n:

neuroepithelial layer

nm:

nuclear masses

pd:

prepyramidal fissure

pr:

fissura prima

pu:

Purkinje cells

t:

tela choroidea

tv:

third ventricle

w:

laminae of white matter

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Authors and Affiliations

  1. Departamento de Ciencias Morfológicas I, Facultad de Medicina, Universidad Complutense, E-28040, Madrid, Spain

    F. Viejo Tirado, A. Peña Melián & J. Puerta Fonollá

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  1. F. Viejo Tirado
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  2. A. Peña Melián
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  3. J. Puerta Fonollá
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Tirado, F.V., Melián, A.P. & Fonollá, J.P. Lectin-binding patterns in the development of the cerebellum. Anat Embryol 189, 169–179 (1994). https://doi.org/10.1007/BF00185775

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