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Extramedullary haemopoiesis of the hypophysis in a beagle

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Abstract

A case of extramedullary haemopoiesis of the hypophysis of a female beagle dog is reported. An investigation by electron microscopy confirmed the presence of cells from the erythroid and myeloid series. This finding was thought to represent prolonged postnatal haemopoiesis in an unusual location.

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References

  • Andersen AC, Goldman M (1970) Growth and development. In: Andersen AC (ed) The beagle as an experimental dog. Iowa State University Press, Ames, USA, p 43

    Google Scholar 

  • Bloom JC, Lewis HB, Sellers TS et al. (1987) The hematopathology of cefonicid and cefazedone-induced blood dyscrasias in the dog. Toxicol Appl Pharmacol 90:143–155

    Google Scholar 

  • Breton-Gorius J, Reyes F (1976) Ultrastructure of human bone marrow cell maturation. Int Rev Cytol 46:251–321

    Google Scholar 

  • Deldar A, Lewis H, Bloom J (1989) Electron microscopic study of the unique features and structural-morphologic relationship of canine bone marrow. Am J Vet Res 50:136–144

    Google Scholar 

  • English RV, Breitschwerdt EB, Grindem CB et al. (1988) Zollinger-Ellison syndrome and myelofibrosis in a dog. J Am Vet Med Assoc 192:1430–1434

    Google Scholar 

  • Fliedner TM, Wandl UB, Calvo W (1982) Medullary and extramedullary hemopoiesis in the dog following wholebody irradiation and autologous transfusion of stem cells. Schweiz Med Wochenschr 112:1424–1429

    Google Scholar 

  • Ishimura K, Hatano M, Iwaki M et al. (1982) Toxicological studies on 2-pyridylmethyl 2-(p-(2-methylpropyl)phenyl) propionate (pimeprofen) (3) 5-week subcutaneous toxicity test in dogs. Pharmacometrics 23:803–832

    Google Scholar 

  • Kuehn NF, Gaunt SD (1986) Hypocellular marrow and extramedullary hematopoiesis in a dog: hematologic recovery after splenectomy. J Am Vet Med Assoc 188:1313–1315

    Google Scholar 

  • Lees GE, Sautter JH (1979) Anemia and osteopetrosis in a dog. J Am Vet Med Assoc 175:820–824

    Google Scholar 

  • Ohtaki T, Imai K, Yoshimura S et al. (1981) 3 Months subacute toxicity of captopril in beagle dogs. J Toxicol Sci 6–247–270

    Google Scholar 

  • O'Keefe DA, Couto CG (1987) Fine-needle aspiration of the spleen as an aid in the diagnosis of splenomegaly. J Vet Intern Med 1:102–109

    Google Scholar 

  • Prasse KW, Crouser D, Beutler E et al. (1975) Pyruvate kinase deficiency anemia with terminal myelofibrosis and osteosclerosis in a beagle. J Am Vet Med Assoc 166:1170–1175

    Google Scholar 

  • Riabov SI (1968) The effect of hypophysis on erythropoieses. Probl Gematol Pereliv Krovi 13(12):39–43

    Google Scholar 

  • Schneider P, Bauer M, Busch U et al. (1990) Experimental pancytopenia of the peripheral blood with granulocytopoietic bone marrow hyperplasia in the beagle dog. Exp Pathol 38:201–215

    Google Scholar 

  • Todd GC, Gibson WR, Morton DM (1976) Toxicology of vindesine deacetyl vinblastine amide in mice rats and dogs. J Toxicol Environ Health 1:843–850

    Google Scholar 

  • Yoneda T, Kawamura Y, Sato K et al. (1980) Subacute toxicity test of cefoperazone in beagle dogs with the intramuscular administration for 3 months. Jpn J Antibiot 33:1056–1083

    Google Scholar 

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Gallas, JF., Rees, J.A. Extramedullary haemopoiesis of the hypophysis in a beagle. Comp Haematol Int 4, 239–241 (1994). https://doi.org/10.1007/BF00185181

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