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Therapie der Karzinoide des Magens

Treatment of carcinoids of the stomach

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Abstract

Carcinoids of the stomach are rare but have gained importance since the introduction of acid secretion inhibitors. The most important type is the tumor occurring in patients with chronic atrophic gastritis with and without pernicious anemia. The tumors are benign and can be treated by local endoscopic or surgical methods. Antrectomy reduces hypergastrinemia and may cause regression of the tumor. Sporadic carcinoids of the gastric antrum are malignant, however, and require radical surgical treatment.

Zusammenfassung

Karzinoide des Magens sind selten und haben erst in den letzten Jahren nach Einführen effektiver Methoden für die Säuresekretionshemmung des Magens Bedeutung erlangt. Die bedeutendste Form stellen Tumoren dar, die bei chronisch-atrophischer Gastritis mit und ohne Perniziosa auftreten. Diese Gruppe der Tumoren ist meist benigne und kann durch lokale endoskopische und chirurgische Maßnahmen behandelt werden. Eine Antrektomie beseitigt die Hypergastrinämie und kann zur Regression der Tumoren führen. Die sporadischen Karzinoide des Magenantrums dagegen sind häufig maligne und bedürfen radikal-chirurgischer Behandlungskonzepte. Interesse erfahren, da eine enge Beziehung zwischen Säuresekretion des Magens und Serumgastrinspiegel auf der einen Seite sowie der Entstehung von Karzinoiden dokumentiert werden konnte [11, 18, 24, 28].

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  1. Abteilung Allgemeine Chirurgie, Universität Tübingen, Hoppe-Seyler-Straße 3, D-72076, Tübingen

    H. D. Becker & A. Gabriel

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Becker, H.D., Gabriel, A. Therapie der Karzinoide des Magens. Langenbecks Arch Chir 381, 18–22 (1996). https://doi.org/10.1007/BF00184250

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