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Measurement of blood flow in rabbit bone transplants

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Summary

The rate of blood flow in free bone grafts in rabbits was monitored for 8 weeks after transplantation using the hydrogen washout technique. Blood flow was present at 2 weeks in both autografts and allografts, although the rate was significantly lower in the allograft compared to the autograft. Autografts showed a rapid increase from 2 to 3 weeks and a maximum flow 4 weeks after transplantation, whereas in allografts the rate of increase was slower. This study has demonstrated that the hydrogen washout technique is a useful method of monitoring blood flow and can be applied to clinical investigations.

Résumé

Le degré de vascularisation des greffes osseuses libres pratiquées ches le lapin a été contrôlé pendant 8 semaines après la transplantation en utilisant la technique de lavage à l'hydrogène. La vascularisation était présente à 2 semaines aussi bien dans les autogreffes que dans les allogreffes. Mais le degré de vascularisation était significativement plus bas dans les allogreffes que dans les autogreffes. La vascularisation des autogreffes augmente rapidement entre la 3ème et la 4ème semaine avec un maximum 4 semaines après la transplantation. Le degré d'accroissement de la vascularisation est plus lent dans les allogreffes. Cette étude démontre que la technique du lavage à l'hydrogène est une méthode utile pour contrôler la vascularisation et qu'elle peut être appliquée en clinique.

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Ogata, K., Kuroki, T. & Sugioka, Y. Measurement of blood flow in rabbit bone transplants. International Orthopaedics 14, 75–78 (1990). https://doi.org/10.1007/BF00183369

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  • DOI: https://doi.org/10.1007/BF00183369

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