Skip to main content

Advertisement

SpringerLink
Log in

Magnetic resonance imaging in malignant bone tumours

  • Published:
International Orthopaedics Aims and scope Submit manuscript

Summary

Complete removal of the tumour without leaving microscopic disease is vital in the management of bone sarcomas. Magnetic resonance imaging now seems to be the best method of depicting the changes produced by the tumour within the bone and surrounding soft tissues. In order to define its reliability, five cases of primary bone sarcomas (Ewing's sarcoma, osteosarcoma, chondrosarcoma) are described where radiographs, bone scans and magnetic resonance images are directly compared to the pathological findings after resection. We conclude that surgical margins should be redefined with respect to the extent and borders of the tumour as depicted by magnetic resonance imaging. This will allow improvement in salvage procedures, but further experience is needed so as not to jeopardise the prognosis by incomplete removal of the tumour.

Résumé

Dans le traitement des sarcomes osseux, l'ablation absolument complète de la tumeur est d'une importance vitale. Actuellement l'imagerie par résonance magnétique semble la méthode de choix pour la détermination des lésions osseuses et de l'invasion des tissus avoisinants. Afin de juger de son utilité, cinq cas de sarcomes osseux (sarcome d'Ewing, ostéosarcome, chondrosarcome) sont décrits pour lesquels la radiographie conventionnelle, la scintigraphie osseuse et l'imagerie par résonance magnétique sont directement comparées aux pièces de résection. Nous enconcluons que les limites de la résection devraient être redéfinies en fonction de l'examen magnétique. Cela permettra d'effectuer des interventions moins radicales; mais une plus longue expérience est encore nécessaire afin de pas aggraver le pronostic des patients par une excision incomplète de la tumeur.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Aisen AM, Martel W, Braunstein EM, Mc Millin KI, Philips WA, Kling TF (1986) MRI and CT evaluation of primary bone and soft tissue tumors. Am J Roentgenol 146: 749–756

    CAS  Google Scholar 

  2. Beltran J, Noto AM, Chakeres DW, Christoforidis AJ (1987) Tumors of the osseous spine: staging with MR imaging versus CT. Radiology 162: 565–569

    Google Scholar 

  3. Chang AE, Matory YL, Dwyer AY, Hill SC, Girton ME, Steintag SM, Knop RH, Frank JA, Hyams D, Doppman JL (1987) Magnetic resonance imaging versus computed tomography in the evaluation of soft tissue tumors of the extremities. Ann Surg 205: 340–348

    Google Scholar 

  4. Davidson RT, Cooke J, Parsons C, Westbury G (1987) Pre-operative assessment of soft tissue sarcomas by computed tomography. Br J Surg 74: 474–478

    Google Scholar 

  5. Hochstetter von AR, Cserhati M, Honegger HP, Groscurth P, Hofmann V (1983) Zurich Bone Sarcoma Study II: Histomorphologic analysis of bone sarcomas following treatment with preoperative chemotherapy. Verh Dtsch Krebs Ges 4: 783 (Abstr). Fischer Stuttgart, New York

    Google Scholar 

  6. Levin DN, Herrmann A, Spraggins T, Collins PA, Dixon LB, Simon MA, Stillman AE (1987) Musculoskeletal tumors: improved depiction with linear combinations of MR images. Radiology 163: 545–459

    Google Scholar 

  7. Madewell JE, Ragsdale BD, Sweet DE (1981) Radiologic and pathologic analysis of solitary bone lesions. Part. I: Internal margins. Radiol Clin North Am 19: 715–748

    Google Scholar 

  8. Mail JT, Cohen MD, Mirkin LD, Provisor AJ (1985) Response of osteosarcoma to preoperative intravenous high-dose methotrexate chemotherapy: CT-evaluation. Am J Roentgenol 144: 89–93

    Google Scholar 

  9. Pettersson H, Gillespy T, Hamlin DJ, Enneking WF, Springfield DS, Andrew ER, Spanier S, Slone R (1987) Primary musculo-skeletal tumors: examination with MR imaging compare with conventional modalities. Radiology 164: 237–241

    PubMed  Google Scholar 

  10. Ragsdale BD, Madewell JE, Sweet DE (1981) Radiologic and pathologic analysis of solitary bone lesions. Part II: Periosteal reaction. Radiol Clin North Am 19: 749–783

    Google Scholar 

  11. Richardson ML (1986) Optimizing pulse sequences for magnetic resonance imaging of the musculo-skeletal system. Radiol Clin North Am 24: 137–177

    Google Scholar 

  12. Rosenthal DI, Scott JA, Mankin HJ, Wismer GL, Brady TJ (1985) Sacrococcygeal chordoma: magnetic resonance imaging and computed tomography. Am J Roentgenol 145: 143–147

    Google Scholar 

  13. Sundaram M, McGuire MH, Herbold DR (1987) Magnetic resonance imaging of osteosarcoma. Skeletal Radiol 16: 23–29

    Google Scholar 

  14. Sundaram M, McGuire MH, Herbold DR, Wolverson MK, Heibers E (1986) Magnetic resonance imaging in planning limb-salvage surgery for primary malignant tumors of bone. J Bone Jt Surg [Br] 68: 809–819

    Google Scholar 

  15. Sweet DE, Madewell JE, Ragsdale BD (1981) Radiologic and pathologic analysis of slitary bone lesions. Part III: Matrix patterns. Radiol Clin North Am 19: 785–814

    Google Scholar 

  16. Totty WG, Murphy WA, Lee JKT (1986) Soft tissue tumors: MR imaging. Radiology 160: 135–141

    Google Scholar 

  17. Vanel D, Lacombe MJ, Couanet D, Kalifa C, Spielmann M, Genin J (1987) Musculoskeletal tumors: follow-up with MR imaging after treatment with surgery and radiation therapy. Radiology 164: 243–245

    Google Scholar 

  18. Yeaser BA, Schiebler ML, Wertheim SB, Schmidt RG, Tors JS, Perosio PM, Dalinka MK (1987) MR images of osteoid osteoma of the talus. J Comput Assist Tomogr 11: 916–917

    Google Scholar 

  19. Zimmer WD, Berquist TH, McLeod RA, Sim FH, Pritchard D, Shives TC, Wold LE, May GR (1985) Bone tumors: magnetic resonance imaging versus computed tomography. Radiology 155: 709–718

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Orthopaedics, University Hospital, Zurich, Switzerland

    G. U. Exner, A. R. von Hochstetter & N. Augustiny

  2. Department of Pathology, University Hospital, Zurich, Switzerland

    A. R. von Hochstetter

  3. Department of Radiology, University Hospital, Zurich, Switzerland

    N. Augustiny & G. von Schulthess

Authors
  1. G. U. Exner
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. A. R. von Hochstetter
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. N. Augustiny
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. G. von Schulthess
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Exner, G.U., von Hochstetter, A.R., Augustiny, N. et al. Magnetic resonance imaging in malignant bone tumours. International Orthopaedics 14, 49–55 (1990). https://doi.org/10.1007/BF00183365

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00183365

Keywords

Search

Navigation