Summary
A total of 17 patients underwent total cystectomy at 1–8 weeks following transurethral contact Nd: YAG laser destruction of bladder tumors (TULD) between February 1984 and December 1990. The laser-irradiated areas were studied pathologically. Five principal results were obtained. First, the irradiated areas were sharply bound from the nonirradiated area and featured ulceration and granulation associated with intensive edema. Second, fibroblast cells and fibrous cells appeared and new vascular growth was manifest; by approx. week 8 postirradiation, carbonized foreign bodies had been incorporated into the granulation and giant cells could be seen ingesting the foreign bodies. Third, neither perforation nor thermal damage to the intestine occurred. Fourth, the irradiated beds were suspected of harboring residual cancer cells in cases at stage T3. Finally, contact irradiation did not result in the transplantation of cancer cells.
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References
Hofstetter A, Frank F (1980) The neodymium: YAG laser in urology. Hoffman-La Roche Co., Ltd., Basel, Switzerland, pp 17–30
Keiditsch E (1981) Histologische Grundlagen der endovesicalen Neodym-YAG Laserbestrahlung. Urologe [A]20:300–304
Kronester A, Staehler G, Weinberg W, Keiditsch E (1981) Risk of intestinal damage from endoscopic neodymium-YAG laser irradiation of bladder tumors. Urologe [A]20:305–309
Pensel J, Hofstetter A, Frank F, Keiditsch E, Rothenberger K (1981) Temporal and spatial temperature profile of the bladder serosa in intravesical Nd: YAG laser irradiation. Eur Urol 7:298–303
Beisland HO, Sander S, Fossberg E (1985) Neodymium: YAG laser irradiation of urinary bladder tumors. Follow-up study of 100 consecutively treated patients. Urology 25:559–563
Smith JA (1986) Treatment of invasive bladder cancer with a neodymium: YAG laser. J Urol 135:55–57
Okada K, Asaoka H, Amagi T, Onoe Y, Kishimoto T (1982) Transurethral neodymium: YAG laser surgery for bladder tumors. Urology 20:404–407
Deikuzono N, Joffe SN (1985) Artificial sapphire probe for contact photocoagulation and tissue vaporization with the Nd: YAG laser. Med Instrum (Baltimore) 19:151–192
Washida H, Sakagami Y, Iwase J, Kato J, Deikuzono N (1987) The contact Nd: YAG laser system in the treatment of bladder cancer: a preliminary report on 48 patients. Lasers Surg Med 7:524–527
Wishnow IK, Johnson ED, Cromeens MD, Gringnon JD, Ayala GA (1989) Acute and chronic effects of neodymium: YAG laser photo-irradiation on the ureteral orifices. Lasers Surg Med [Suppl] 1:53
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Washida, H., Watanabe, H., Noguchi, Y. et al. Tissue effects in the bladder wall after contact Nd: YAG laser irradiation for bladder tumors. World J Urol 10, 115–119 (1992). https://doi.org/10.1007/BF00183145
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DOI: https://doi.org/10.1007/BF00183145