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Lhermitte's sign as a presenting symptom of primary spinal cord tumor

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Summary

We describe a previously healthy 29 year-old man who developed Lhermitte's sign, a shock-like or electric sensation, transmitted down the spine, which occurred during neck flexion or rotation. Evaluation demonstrated an intrinsic, fusiform mass extending from c5 to c7. At operation, the mass was completely removed and found to be a low-grade ependymoma. The sensory phenomena of Lhermitte's sign were most likelycaused by tumor-induced distortion and demyelination of cervical dorsal column sensory axons. Lhermitte's sign is most prevalent in patients with multiple sclerosis, cervical spondylotic myelopathy, cisplatin neurotoxicity, cervical radiation injury, and neck trauma. Rarely, Lhermitte's sign occurs with spinal cord compression from epidural or subdural tumor. This patient is the first reported case of an intrinsic spinal cord tumor to present with Lhermitte's sign.

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Authors and Affiliations

  1. Departments of Neurology and Neuroscience, The Ohio State University Hospitals and Arthur James Cancer Hospital and Research Institute, Columbus, Ohio

    Herbert B. Newton

  2. Division of Neurosurgery, The Ohio State University Hospitals and Arthur James Cancer Hospital and Research Institute, Columbus, Ohio

    Gary L. Rea

Authors
  1. Herbert B. Newton
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  2. Gary L. Rea
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Newton, H.B., Rea, G.L. Lhermitte's sign as a presenting symptom of primary spinal cord tumor. J Neuro-Oncol 29, 183–188 (1996). https://doi.org/10.1007/BF00182142

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  • DOI: https://doi.org/10.1007/BF00182142

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