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Malignant sacrococcygeal teratoma: improved survival with chemotherapy


Between 1954 and 1985, 15 cases of malignant sacrococcygeal teratoma were treated in our institution. Median age at presentation was 20 months (range 9–46 months); there were 14 females and 1 male. Six cases presenting prior to 1970 were treated without chemotherapy with a median survival of 2 months (range 1–7 months). Five patients treated from 1971 to 1979 had tumour excision plus vincristine, actinomycin D, and cyclophosphamide (VAC). Three received radiotherapy in addition and median survival was 11 months (range 0–31 months). Four patients presenting since 1980 had chemotherapy alone after tumour excision. 1 receiving VAC and adriamycin and the remaining patients cisplatinum, bleomycin, and VP16. All these are alive and disease free (median follow-up 27 months; range 15–96 months). It is concluded that initial surgery aimed at complete excision followed by aggressive chemotherapy gives good results.

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Shanbhogue, L.K.R., Gough, D.C.S. & Jones, P.M. Malignant sacrococcygeal teratoma: improved survival with chemotherapy. Pediatr Surg Int 4, 202–204 (1989).

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Key words

  • Malignant sacrococcygeal teratoma
  • Excision
  • Chemotherapy