Abstract
The purpose of the present study was to determine the validity of antigen non-specific immunological tests in order to develop a risk-clinical profile of patients with immune-mediated inner ear pathology. The study was carried out on 38 patients with progressive sensorineural hearing loss and a control group of 26 subjects. Serological testing was used to determine cell activation complexes. In patients with hearing loss, T -lymphocyte subpopulations were found to have an increase in cytotoxic T-cells when compared to T-helper, but only for interleukin-2 receptor expression. This difference was significant between patients and the control group. Present findings suggest that T-lymphocyte “early” marker is of particular interest for developing a risk-clinical profile of patients with sensorineural progressive hearing loss of immune origin.
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Savastano, M., Raffael, C., Andreoli, C. et al. Antigen non-specific immunological tests in progressive sensorineural hearing loss. Eur Arch Otorhinolaryngol 251, 275–277 (1994). https://doi.org/10.1007/BF00181884
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DOI: https://doi.org/10.1007/BF00181884