Abstract
A nerve-sheath myxoma beneath the dermis in the arm of a 5-year-old boy is reported. The tumor had developed on the site of chicken-pox vaccination the patient had received 2 years previously, and a foreign-body granuloma involving a nerve-fiber bundle was seen adjavent to the tumor. On the basis of previous reports, it is doubtful whether the varicella-zoster virus is tumorigenic. The present case suggests a possible relationship between the development of this tumor and factors associated with the vaccination.
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References
Barnhill RL, Dickersin GR, Nickeleit V, et al. (1991) Studies on the cellular origin of neurothekeoma. Clinical, light microscopic, immunohistochemical, and ultrastructural observations. J Am Acad Dermatol 25: 80–88
Enzinger FM, Weiss SW (1988) Soft tissue tumors, 2nd edn, Mosby, St Louis, pp735–741, 769–770
Gelb L, Dohner D (1984) Varicella-zoster virus-induced transformation of mammalian cells in vitro. J Invest Dermatol 83: 77s-81s
harkin JC, Reed RJ (1969) Tumors of the peripheral nervous system. (Atlas of tumor pathology, 2nd ser., fasc. 3), Armed Forces Institute of Pathology, Washington, pp 60–64
Hendrick MJ, Goldschmidt MH, Shofer FS, et al. (1992) Postvaccinal sarcomas in the cat. Epidemiology and electron probe microanalytical identification of aluminum. Cancer Res 52: 5391–5394
Pulitzer DR, Reed RJ (1985) Nerve-sheat myxoma (perineurial myxoma). Am J Dermatopathol 7: 409–421
Rosai J (1989) Surgical pathology, 7th edn. Mosby, St Louis, pp 1569–1571
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Nokubi, M., Makino, S., Kawai, T. et al. Nerve-sheath myxoma on a chicken-pox vaccination site. Pediatr Surg Int 9, 534–535 (1994). https://doi.org/10.1007/BF00179466
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DOI: https://doi.org/10.1007/BF00179466