Summary
The development of the cardio-pulmonary innervation was studied in whole-mount specimens of chick embryos stained with the anti-neurofilament protein (NFP) antibody. From the morphological point of view, vagal branches could be classified into two categories, i.e., the branchial branches primarily related to the pharnygeal arches, and intestinal arborization derivatives which are associated primarily with the primitive gut. The former consisted of the superior cardiac branch innervating the truncus arteriosus of the heart, and the latter, the sinal branch, pulmonary branches as well as recurrent nerve and the other intestinal branches. The superior cardiac branch at first develops as a pair of branchial branches which passes into the truncus arteriosus at stage 25, and later rotates along the aortic arch 6, thus making an asymmetrical configuration by stage 27. The sinal branch is a medial branch which first develops at stage 24. It arises from the junction of each intestinal arborization in close association with the pulmonary branch.
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References
Barry A (1951) The aortic arch derivatives in the human adult. Anat Rec 111:221–238
Cyon E, Ludwig C (1867) Die Reflexe eines der sensiblen Nerven des Herzens auf die motorischen der Blutgefässe. Arb Physiol Anat Leipzig, 1: (cited in Perman)
D'Amico-Martel M, Noden DM (1983) Contributions of placodal and neural crest cells to avian cranial peripheral ganglia. Am J Anat 166:445–468
Davies AM (1987) Molecular and cellular aspects of patterning sensory neuron connections in the vertebrate nervous system. Development 101:185–208
Fedde MR, Burger RE, Kitchell RL (1963) Localization of vagal afferents involved in the maintenance of normal avian respiration. Poult Sci 42:1224–1236
Fukuyama U (1970) Vagal innervation of respiratory organs (in Japanese). Clin Resp Physiol 3:109–125
Fukuyama U (1982) Macroscopic anatomy of human cardiac nerves (in Japanese). Acta Anat Nippon 57:357–380
Fürbringer M (1897) Spino-occipital Nerven der Selachier und Holocepahlen und ihre vergleichende Morphologie. Festschrift für C. Gegenbaur, Leipzig, 1897:351–788
Goodrich ES (1958) Studies on the structure and development of vertebrates. Dover
Hamburger V, Hamilton HL (1951) A series of normal stages in the development of the chick embryo. J Morphol 88:49–67
Hannemen E, Trevarrow B, Metcalfe WK, Kimmel CB, Westrfield M (1988) Segmental pattern of development of the hindbrain and spinal cord of the zebrafish embryo. Development 103:49–58
Hirakow R, Miki S (1971) Phylogenetic observations on the cardiac nerves of vertebrates. Proc Japan Acad 47:225–230
His W jr (1891) Abh math-phys C1 Königl Sachs Ges Wiss 18:1
Ishikawa Y, Zukeran C, Kuratani S, Tanaka S (1986) A staining procedure for nerve fibers in whole-mount preparations of the medaka and chick embryos. Acta Histochem Cytochem 19:775–783
Johnston JB (1905) The morphology of the vertebrate head from the viewpoint of the functional divisions of the nervous system. J Comp Neurol 15:175–275
Kastschenko N (1887) Das Schlundspaltengebiet des Hühnchens. Arch Anat Physiol 1887:258–300
Kimmel CB, Sepich DS, Trevarrow B (1988) Development of segmentation in zebrafish. Development 104:197–207
Kirby ML (1987) Cardiac morphogenesis — recent research advances. Pediatr Res 21:219–224
Kirby ML (1988) Nodose placode contributes autonomic neurons to the heart in the absence of cardiac neural crest. J Neurosci 8:1089–1095
Kirby ML, Bockman DE (1984) Neural crest and normal development: a new perspective. Anat Rec 209:1–6
Kirby ML, Stewart DE (1983) Neural crest origin of cardiac ganglion cells in the chick embryo: identification and extirpation. Dev Biol 97:433–443
Kirby ML, McKenzie JW, Weidman TA (1980) Developing innervation of the chick heart: a histofluorescence and light microscopic study. Anat Rec 196:333–340
Kuratani S (1990) Development of glossopharyngeal nerve branches in the early chick embryo with special reference to Morphology of the Jacobson's anastomosis. Anat Embryol 181 (in press)
Kuratani S, Tanaka S (1990) Peripheral development of avian trigeminal nerves. Am J Anat 187:65–80
Kuratani S, Tanaka S, Ishikawa Y, Zukeran C (1988a) Early development of the hypoglossal nerve in the chick embryo as observed by the whole-mount nerve staining method. Am J Anat 182:155–168
Kuratani S, Tanaka S, Ishikawa Y, Zukeran C (1988b) Early development of the facial nerve in the chick embryo with special reference with the development of the chorda tympani. Am J Anat 182:169–182
Le Douarin NM (1982) The Neural Crest. Cambridge University Press, Cambridge London New York New Rochelle Melbourne Sydney
Lewis J (1989) Genes and segmentation. Nature 341:382–383
Licata RH (1954) The human embryonic heart in the ninth week. Am J Anat 94:73–125
Lumsden A, Keynes R (1989) Segmental patterns of neuronal development in the chick hindbrain. Nature 337:424–428
Mizeres NJ (1963) The cardiac plexus in man. Am J Anat 112:141–151
Muratori G (1933) Osservazioni sulla base istologica dei riflessi aortico e carotideo. Atti Soc Med Chir Padova 11:213–217 (cited in Fedde et al. 1963)
Narayanan CH, Narayanan Y (1980) Neural crest and placodal contribution in the development of the glossopharyngeal-vagal complex in the chick. Anat Rec 196:71–82
Nilsson S (1983) Anatomy of the vertebrate autonomic nervous systems. In: Nilsson S (ed) Autonomic nerve function in vertebrates. Springer, Berlin Heidelberg New York, pp 6–40
Nonidez JF (1935) The presence of depressor nerves in the aorta and carotid of birds. Anat Rec 62:47–73 (cited in Fedde et al. 1963)
Ogawa T (1952) On the cardiac nerves of some cetacea, with special reference to those of Berardius bairdii Steineger. Sci Rep Whales Res Inst 7:1–22 (cited in Hirakow 1987)
Rickenbacher J, Müller E (1979) The development of cholinergic ganglia in chick embryo heart. Anat Embryol 155:253–258
Shaner RF (1930) On the development of the nerves to the mammalian heart. Anat Rec 46:23–39
Tanaka S (1976) Facial nerve of the shark (Musterus manazo) and its comparison with the glossopharyngeal nerve. Acta Anat Nippon 51:1–16
Tanaka S, Nakao T (1979) A macroscopical study of the vagal nerve of sharks (Musterus manazo) with special reference to morphological features of its branchial branches (in Japanese). Acta Anat Nippon 54:307–321
Thompson RP, Abercrombie V, Wong M (1987) Morphogenesis of the truncus arteriosus of the chick embryo heart: movements of autoradiographic tattoos during septation. Anat Rec 218:434–440
Walkey GK, Bower AJ (1981) The distal vagal ganglion of the hen (Gallus domesticus). A histological and physiological study. J Anat 132:95–115
Watanabe T (1960) Comparative and topographical anatomy of the fowl. VII. On the peripheral course of the vagus nerve in the fowl (in Japanese). Jap J Vet Sci 22:145–154
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Kuratani, S., Tanaka, S. Peripheral development of the avian vagus nerve with special reference to the morphological innervation of heart and lung. Anat Embryol 182, 435–445 (1990). https://doi.org/10.1007/BF00178908
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DOI: https://doi.org/10.1007/BF00178908