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Plasma carcinoembryonic antigen as an indicator of cerebral metastases

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Abstract

Four patients in whom the plasma CEA reflected the clinical course of intracranial disease are presented. We conclude that a search to explain an elevated CEA should include the central nervous system. In addition, in selected patients with brain metastases the plasma CEA is a helpful indicator of tumor control and of its response to radiation and chemotherapy.

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References

  1. Tormey DC, Davis TE, Waalkes TP: Tumor markers. In: Carter SK, Glatstein E, Livingston RB (eds) Principles of Cancer Treatment. McGraw-Hill Inc. 1982, pp 170–177

  2. Lokich JJ, Zamcheck N, Lowenstein M: Sequential carcinoembryonic antigen levels in the therapy of metastatic breast cancer. Annals Internal Med 89:902–906, 1978

    Google Scholar 

  3. Wasserstrom WR, Schwartz MK, Fleisher M, Posner JB: Cerebrospinal fluid biochemical markers in central nervous system tumors: A review. Annals of Clinical and Laboratory Science. Vol. 11, No. 3, 239–251, 1981

    Google Scholar 

  4. Falkson HC, Vander Watt JJ, Portugal MA, Schoeman HS, Falkson G: Role of plasma carcinoembryonic antigen in evaluating patients with breast cancer treated with adjuvant chemotherapy. Cancer Treat Rep 63(8):1303–1309,1979

    Google Scholar 

  5. Falkson HC, Van der Watt JJ, Portugal MA, Pitout MJ, Falkson G: Carcinoembryonic antigen in patients with breast cancer. Cancer 42:1308–1313,1978

    Google Scholar 

  6. Loprinzi CL, Tormey DC, Rasmussen P, Falkson G, Davis TE, Falkson HC, Chang AYC: Prospective evaluation of carcinoembryonic antigen levels and alternating chemotherapeutic regimens in metastatic breast cancer. J Clin Oncol 4:45–56,1986

    Google Scholar 

  7. Mughal AW, Hortobagyi GN, Fritsche HA, Buzdar AU, Yap HY, Blumenschein GR: Serial plasma carcinoembryonic antigen measurements during treatment of metastatic breast cancer. JAMA 249(14):1881–1886, 1983

    Google Scholar 

  8. Haagensen DE, Barry WF, McCook TA, Giannola J, Ammirata S, Wells SA: The value of serial plasma levels of carcinoembryonic antigen and gross cyst disease fluid protein in patients with breast carcinoma and osseous metastases. Annals of Surgery 191(5):599–603,1980

    Google Scholar 

  9. Klee GG, Tallman RD, Goellner JR, Yanagihara T: Elevation of carcinoembryonic antigen in cerebrospinal fluid among patients with meningeal carcinomatosis. Proc Mayo Clinic 61(1):9–13,1986

    Google Scholar 

  10. Snitzer LS, McKinney EC, Tejada F, Sigel MM, Rosomoff HL, Zubrod CG: Cerebral metastases and carcinoembryonic antigen in CSF. N Engl J Med 293(21), 1975

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Eden, E.A., Muggia, J.M., Hiesiger, E.M. et al. Plasma carcinoembryonic antigen as an indicator of cerebral metastases. J Neuro-Oncol 8, 281–287 (1990). https://doi.org/10.1007/BF00177362

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  • DOI: https://doi.org/10.1007/BF00177362

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