Abstract
A 5-year-old girl with stage IV neuroblastoma with diesseminated marrow involvement was treated with high-dose chemotherapy and autografts with peripheral blood stem/progenitor cells (PBSC), without local or total-body irradiation. After PBSC autograft, hematologic recovery was complete. Without further anticancer therapy, she remained tumor-free for 38 months until a local recurrence was identified. This case illustrates that late relapse can occur in advanced-stage neuroblastoma after long-term remission following high-dose chemotherapy without irradiation.
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Correspondence to: H. Takehara
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Takehara, H., Takaue, Y., Watanabe, T. et al. Relapse of neuroblastoma 38 months after high-dose chemotherapy and peripheral blood stem-cell autografts. Pediatr Surg Int 8, 443–444 (1993). https://doi.org/10.1007/BF00176742
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DOI: https://doi.org/10.1007/BF00176742