Summary
This article reports on the use of short-hard pulse and spin-lock pulse combinations giving a binomial-like frequency response for the measurement of NMR spectra in aqueous solutions of quite dilute samples. The pulse sequence proposed provides excellent water suppression and does not introduce any linear or higher order phase errors. Application to the measurement of 2D NOESY data of a 0.25 mM solution of a double-stranded DNA fragment is presented.
This is a preview of subscription content, log in via an institution to check access.
References
Guéron, M., Plateau, P., Kettani, A. and Decorps, M. (1992) J. Magn. Reson., 96, 541–550.
Holak, T.A., Wiltscheck, R. and Ross, A. (1992) J. Magn. Reson., 97, 632–636.
Hore, P.J. (1983) J. Magn. Reson., 45, 283–300.
Hoult, D.I. (1976) J. Magn. Reson. 21, 337–347.
Kubinec, M.G. and Wemmer, D.E. (1992) J. Am. Chem. Soc., 114, 8739–8740.
Messerle, B.A., Wider, G., Otting, G., Weber, C. and Wüthrich, K. (1989) J. Magn. Reson., 85, 608–613.
Otting, G. and Wüthrich, K. (1989) J. Am. Chem. Soc., 111, 1871–1875.
Otting, G., Liepinsh, E. and Wüthrich, K. (1991) Science, 254, 974–980.
Otting, G., Liepinsh, E. and Wüthrich, K. (1992) J. Am. Chem. Soc., 114, 7093–7095.
Otting, G., Liepinsh, E., FarmerII, B.T. and Wüthrich, K. (1991) J. Biomol. NMR, 1, 209–215.
Piotto, M., Saudek, V. and Sklenàr, V. (1992) J. Biomol. NMR, 2, 661–665.
Piveteau, D., Delsuc, M-A., Guittet, E. and Lallemand, J.-Y. (1987) J. Magn. Reson., 71, 347–348.
Plateau, P. and Guéron, M. (1982) J. Am. Chem. Soc., 104, 7310–7311.
Plateau, P., Dumas, C. and Guéron, M. (1983) J. Magn. Reson., 54, 46–53.
Redfield, A.G., Kunz, S.D. and Ralph, E.K. (1975) J. Magn. Reson., (19), 114–117.
Sklenàr, V., Tschudin, R. and Bax, A. (1982) J. Magn. Reson., 75, 352–357.
Sklenàr, V. and Starcuk, Z. (1982) J. Magn. Reson., 50, 495–501.
Smallcombe, S.H. (1993) J. Am. Chem. Soc., in press.
Sodano, P. and Delepierre, M. (1993) J. Magn. Reson., 103, in press.
Sørensen, O.W., Eich, G.W., Levitt, M.H., Bodenhausen, G. and Ernst, R.R. (1983) Prog. NMR Spectrosc., 16, 163–192.
Tate, S., Masui, Y. and Inagaki, F. (1991) J. Magn. Reson., 94, 394–400.
Zuiderweg, E.R.P., Hallenga, K. and Olejniczak, E.T. (1986) J. Magn. Reson., 70, 336–343.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Sodano, P., Delepierre, M. Binomial frequency response to non-binomial pulse sequences for efficient water suppression. J Biomol NMR 3, 471–477 (1993). https://doi.org/10.1007/BF00176012
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00176012