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Current considerations in the etiology and diagnosis of tympanosclerosis

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Abstract

Current concepts of formation of tympanosclerosis in the middle ear are reviewed, as are various clinical considerations. Ultrastructural changes are discussed. A differential diagnosis includes disorders affecting middle ear sound conduction, with the most prevalent involving otosclerosis and cholesteatoma.

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References

  1. Aboulker P, Demaldent JE (1975) Tympanosclérose. Encycl Med Chir ORL (Paris) 20182 G109

  2. Anderson HC (1976) Matrix vesicles calcification introduction. Fed Proc 35:105–108

    Google Scholar 

  3. Austin DF (1988) Reconstructive techniques for tympanosclerosis. Ann Otol Rhinol Laryngol 97:670–674

    Google Scholar 

  4. Austin DF (1991) Chronic ear disease. In: Ballenger JJ (ed) Diseases of the nose, throat, ear, head and neck, 14th edn. Lea and Febiger, Philadelphia, pp 1109–1118

    Google Scholar 

  5. Bernstein JM, Reisman R (1974) The role of acute hypersensitivity in secretory otitis media. Trans Am Acad Ophthalmol Otolaryngol 78:120–127

    Google Scholar 

  6. Bhaya MH, Schachren PA, Morizono T, Paparella MM (1993) Pathogenesis of tympanosclerosis. Otolaryngol Head Neck Surg 109:413–420

    Google Scholar 

  7. Bonucci E (1971) The locus of initial calcification in cartilage and bone. Clin Orthop 78:108–139

    Google Scholar 

  8. Bremond G, Bonnaud G, Magnan J (1985) La tympanosclérose. Encycl Med Chir ORL (Paris) 20182 G 10

  9. Bremond G, Bébéar JP, Darrouzet V, Deguine C, Martin C (1989) La tympanosclérose. J Fr ORL 38:400–410

    Google Scholar 

  10. Brown MJKM, Richards SH, Ambegaokar AG (1978) Grommets and glue ear; a 5-year follow-up of a controlled trial. Proc R Soc Med 71:353–356

    Google Scholar 

  11. Cassebohm IF (1734) Tractatus quatuor anatomici de aure humana. Halae Magdeburgicae

  12. Chang IW (1969) Tympanosclerosis. Electron microscopic study. Acta Otolaryngol (Stockh) 68:62–72

    Google Scholar 

  13. Chang I, Chang C, Lim S (1991) Long term results in surgery for advanced tympanosclerosis; long term results and indications in otology and otoneurosurgery. In: Charachon R, Garcia-Ibanez E (eds) Proceedings of the Politzer Society. Kugler, pp 223–227. Cited in: Lacher G (1992) La tympanosclérose: presentation et épidémiologie. Rencontres Institut Georges Portmann (Bordeaux) 5–7

  14. Charachon R, Roux O, Dumas G, Chanel Y (1981) La tympanosclérose: aspect clinique de la tympanoscl6rose. Rencontres Institut Georges Portmann (Bordeaux) 21–23

  15. Dubreuil C (1992) La tympanosclérose: la pathogénie de la tympanosclérose. Rencontres Institut Georges Portmann (Bordeaux) 11–15

  16. Emmett JL, Shea JJ (1978) Surgical treatment of tympanosclerosis. Laryngoscope 88:1642–1648

    Google Scholar 

  17. Ferlito A (1979) Histopathogenesis of tympanosclerosis. J Laryngol Otol 93:25–37

    Google Scholar 

  18. Friedmann I (1971) Tympanosclerosis. Ann Otol Rhinol Laryngol 80:411–413

    Google Scholar 

  19. Friedmann I, Galey FR (1980) Initiation and stages of mineralization in tympanosclerosis. J Laryngol Otol 94:1215–1229

    Google Scholar 

  20. Friedmann I, Hodges GM, Graham M (1980) Tympanosclerosis, an electron microscopic study of matrix vesicles. Ann Otol Rhinol Laryngol 89 [Suppl 68]:241–245

    Google Scholar 

  21. Gibb AG (1971) Tympanosclerosis. Acta Otorhinolaryngol Belg 25:956–964

    Google Scholar 

  22. Gibb AG (1973) Tympanosclerosis. In: Arslan M, Ricci V (eds) Proceedings of the 10th World Congress in Otorhinolaryngology. International Congress Series No 337. Excerpta Medica, Amsterdam, pp 353–355

    Google Scholar 

  23. Gibb AG (1976) President's address. Tympanosclerosis. Proc R Soc Med 69:155–162

    Google Scholar 

  24. Gibb AG (1979) Non-suppurative otitis media. In: Ballantyne J, Groves J (eds) Scott Brown's Diseases of the ear, nose and throat, 4th edn, vol 2. Butterworths, London, pp 220–234

    Google Scholar 

  25. Gibb AG (1983) Tympanosclerosis. J Laryngol Otol [Suppl] 8:63–67

    Google Scholar 

  26. Giddings NA, House JW (1992) Tympanosclerosis of the stapes: hearing results for various surgical treatments. Otolaryngol Head Neck Surg 107:644–650

    Google Scholar 

  27. 28.Gieseking R (1966)Mesenchymale Gewebe und ihre Reaktionsformen im elektronenoptischen Bild. Veröffentlichungen aus der morphologischen Pathologie. Fischer, Stuttgart

    Google Scholar 

  28. Gormley PK (1987) Stapedectomy in tympanosclerosis. Am J Otol 8:123–130

    Google Scholar 

  29. Gristwood RE, Venables WN (1982) Cholesteatoma and tympanosclerosis. Proceedings of the 2nd International Conference on cholesteatoma and mastoid surgery. Kugler, Amsterdam, pp 133–137

    Google Scholar 

  30. Grüber J (1888) Lehrbuch der Ohrenheilkunde. Cited in: Plester D (1972) Tympanosclerosis. J Otolaryngol Soc Aust 3:325–326

    Google Scholar 

  31. Guilford F (1963) Preoperative evaluation in chronic ear disease. Arch Otolaryngol 78:271–276

    Google Scholar 

  32. Gunderson T (1965) Tympanosclerosis. Acta Otolaryngol (Stockh) 60:506–514

    Google Scholar 

  33. 34.Habermann J (1892) Pathologische Anatomie des Ohres. In: Schwartze H (ed) Handbuch der Ohrenheilkunde, vol 1. Vogel, Leipzig, pp 203–302

    Google Scholar 

  34. Harris I (1961) Tympanosclerosis; a revived clinico-pathologic entity. Laryngoscope 71:1488–1533

    Google Scholar 

  35. Harris I, Weiss L (1962) Tympanosclerosis; superficial and embedded forms. Trans Am Acad Ophthalmol Otolaryngol 66:683–714

    Google Scholar 

  36. House WF, Sheehy JL (1960) Tympanosclerosis. Arch Otolaryngol 72:308–313

    Google Scholar 

  37. Hybasek I (1969) Relation of otitis media chronica secretorica to tympanosclerosis. Sborn Ved Prac Lek Fak Karlovy Univ Hradei Kralov 12:135–140

    Google Scholar 

  38. Igarashi M, Konishi S, Alford BR, Guilford FR (1970) The pathology of tympanosclerosis. Laryngoscope 80:233–243

    Google Scholar 

  39. Katchburian E (1973) Membrane-bound bodies as initiators of mineralization of dentine. J Anat 116:285–302

    Google Scholar 

  40. Kinney SE (1978) Postinflammatory ossicular fixation in tympanoplasty. Laryngoscope 88:821–838

    Google Scholar 

  41. Lacher G (1992) La tympanoscl6rose: presentation et épidémi-ologie. Rencontres Institut Georges Portmann (Bordeaux) 5–7

  42. Lendrum AC (1963) The hypertensive diabetic kidney as a model of the so-called collagen diseases. Can Med Assoc J 88:442–452

    Google Scholar 

  43. Lesser THJ, Williams KR, Skinner DW (1988) Tympanosclerosis, grommets and shear stresses. Clin Otolaryngol 13:375–380

    Google Scholar 

  44. Lildholdt T (1983) Ventilation tubes in secretory otitis media. Acta Otolaryngol (Stockh) 398:4–28

    Google Scholar 

  45. Lim DJ (1968) Tympanic membrane: electron microscopic observation. Acta Otolaryngol (Stockh) 66:181–198

    Google Scholar 

  46. Mackinnon DM (1971) The sequel to myringotomy for exudative otitis media. J Laryngol Otol 85:773–793

    Google Scholar 

  47. Mann W, Riede UN, Jonas I, Beck C (1980) The role of matrix vesicles in the pathogenesis of tympanosclerosis. Acta Otolaryngol(Stockh)89:43–52

    Google Scholar 

  48. Mawson SR, Fagan P (1972) Tympanic effusions in children. Long term results of treatment by myringotomy aspiration and indwelling tubes (grommets). J Laryngol Otol 92:105–119

    Google Scholar 

  49. Michaels L (1987) Ear nose and throat histopathology. Springer, London Berlin Heidelberg, pp 46–47

    Google Scholar 

  50. Møller P (1981) Tympanosclerosis of the ear drum. A scanning electron microscopic study. Acta Otolaryngol (Stockh) 91:215–221

    Google Scholar 

  51. Møller P (1984) Tympanosclerosis of the ear drum in secretory otitis media. Acta Otolaryngol [Suppl] (Stockh) 414:171–177

    Google Scholar 

  52. Morgan WC (1977) Tympanosclerosis. Laryngoscope 87 1821–1825

    Google Scholar 

  53. Parker AJ, Maw AR (1990) Intratympanic membrane bleeding after grommet insertion and tympanosclerosis. Clin Otolaryngol 15:203–207

    Google Scholar 

  54. Plester D (1972) Tympanosclerosis. J Otolaryngol Soc Aust 3 325–326

    Google Scholar 

  55. Politzer A (1883) A textbook of the diseases of the ear and adjacent organs. Cassells JP (trans and ed). Bailliere Tindall Cox, London

  56. Pomeroy OD (1883) The diagnosis and treatment of diseases of the ear. Bermingham, New York

    Google Scholar 

  57. Ruah CB, Schachern PA, Zelterman D, Paparella MM (1991) Age-related changes in the human tympanic membrane. Arch Otolaryngol Head Neck Surg 117:627–634

    Google Scholar 

  58. Sade J (1967) Ciliary activity and middle ear clearance. Arch Otolaryngol 86:128–135

    Google Scholar 

  59. Scherft JP (1978) The lamina limitans of the organic bone matrix: formation in vitro. J Ultrastruct Res 64: 173–181

    Google Scholar 

  60. Schiff M (1983) Tympanosclerosis: clinical implications of the theory of pathogenesis. Ann Otol Rhinol Laryngol 92:635–639

    Google Scholar 

  61. Schiff M, Poliquin JF, Catanzaro A, Ryan AF (1980) Tympanosclerosis. A theory of pathogenesis. Ann Otol Rhinol Laryngol 89 [Supp170]:1–16

    Google Scholar 

  62. Schuknecht HF (1974) Pathology of the ear. Harvard University Press, Cambridge, Mass

    Google Scholar 

  63. Sheehy JL, House WF (1962) Tympanosclerosis. Arch Otolaryngol 76:151–157

    Google Scholar 

  64. Skinner DW, Lesser THJ, Richards SH (1988) A 15 year follow up of a controlled trial of the use of grommets in glue ears. Clin Otolaryngol 13:341–346

    Google Scholar 

  65. Slack RW, Maw AR, Capper JWR, Kelly S (1984) Prospective study of tympanosclerosis developing after grommet insertion. J Laryngol Otol 98:771–774

    Google Scholar 

  66. Smyth GDL (1972) Tympanosclerosis. J Laryngol Otol 86:9–14

    Google Scholar 

  67. Sorensen H, True O (1972) Histology of tympanosclerosis. Acta Otolaryngol (Stockh) 73:18–26

    Google Scholar 

  68. Sterkers JM, Sterkers O, Corlieu P (1979) Résultats de la chirurgie dans la tympanosclerose (77 cas). J Fr ORL 28:239–242

    Google Scholar 

  69. St John Roosa DB (1891) A practical treatise on diseases of the ear. Wood, New York

    Google Scholar 

  70. Surján I, Juhász J (1971) Histopathological investigations of the bone and of the ossicles in cases of tympanosclerosis. Symp ORL Jug 1–3:207–215

    Google Scholar 

  71. Swartz JD, Goodman RS, Russell KB, Marlowe FI, Wolfson RJ (1983) High resolution computed tomography of the middle ear and mastoid (part 2). Radiology 148:455–459

    Google Scholar 

  72. Swartz JD, Wolfson RJ, Marlowe FI, Popky GL (1985) Postinflammatory ossicular fixation: CT analysis with surgical correlation. Radiology 154:697–700

    Google Scholar 

  73. 74.Tos M, Bak-Pedersen K (1974) Middle ear mucosa in tympanosclerosis. J Laryngol Otol 88:119–126

    Google Scholar 

  74. Tos M, Stangerup SE (1989) Hearing loss in tympanosclerosis caused by grommets. Arch Otolaryngol Head Neck Surg 115:931–935

    Google Scholar 

  75. Tos M, Bonding P, Poulsen G (1983) Tympanosclerosis of the drum in secretory otitis after insertion of grommets. A prospective, comparative study. J Laryngol Otol 97:489–96

    Google Scholar 

  76. Tos M, Stangerup SE, Jensen SH, Sorensen CH (1984) Spontaneous course of secretory otitis and changes of the eardrum. Arch Otolaryngol 110:281–289

    Google Scholar 

  77. Tos M, Lau T, Arndal H, Plate S (1990) Tympanosclerosis of the middle ear: late results of surgical treatment. J Laryngol Otol 104:685–689

    Google Scholar 

  78. 79.Toynbee J (1860) The diseases of the ear: their nature, diagnosis and treatment. Churchill, London

    Google Scholar 

  79. Tröltsch AF von (1869) Lehrbuch der Ohrenheilkunde. Vogel, Leipzig

    Google Scholar 

  80. Veltri RW, Sprinkle PM (1976) Secretory otitis media: an immune complex disease. Ann Otol Rhinol Laryngol 85 [Suppl 25]:135–159

    Google Scholar 

  81. Walb H (1893) Krankheiten der Paukenhohle und der Tuba Eustachii. In: Schwartze H (ed) Handbuch der Ohrenheilkunde, vol 2. Hirschwald, Berlin, pp 168–298

    Google Scholar 

  82. Wielinga EWJ, Kuijpers W, Tonnaer ELGM, Jap PHK (1988) An experimental model for tympanosclerosis: a preliminary report. Acta Otolaryngol (Stockh) 105:537–542

    Google Scholar 

  83. Willis R (1972) Cited in: Plester D (1972) Tympanosclerosis. J Otolaryngol Soc Aust 3:325–326

    Google Scholar 

  84. Zöllner F (1956) Tympanosclerosis. J Laryngol Otol 70:77–85

    Google Scholar 

  85. Zöllner F (1963) Tympanosclerosis. Arch Otolaryngol 78:538–544

    Google Scholar 

  86. Zöllner F (1969) Tympanosclerosis. Arch Otolaryngol 89:207–210

    Google Scholar 

  87. Zöllner F, Beck C (1955) Die Paukensklerose. Z Laryngol Rhinol Otol 34:137–143

    Google Scholar 

  88. Zollone AZ, Teti A, lurato S (1983) Metaplasic bone tissue in tympanosclerosis. Acta Otolaryngol (Stockh) 95:554–559

    Google Scholar 

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  1. Department of Otolaryngology, National University Hospital, National University of Singapore, 0511, Lower Kent Ridge Road, Singapore

    A. G. Gibb & Y. T. Pang

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Gibb, A.G., Pang, Y.T. Current considerations in the etiology and diagnosis of tympanosclerosis. Eur Arch Otorhinolaryngol 251, 439–451 (1994). https://doi.org/10.1007/BF00175993

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