References
Sullivan AK, Holdright DR, Wright CA, Sparrow JL, Fox KM. Characterisation and follow-up of patients with chest pain and normal coronary arteries. J Am Coll Cardiol 1993;21: 317A
Kemp HG. Left ventricular function in patients with the anginal syndrome and normal coronary arteriograms. Am J Cardiol 1973;32: 375–376
Legrand V, Hodgson JM, Bates ER, Aueron FM, Mancini GBJ, Smith JS, Gross MD, Vogel RA. Abnormal coronary flow reserve and abnormal radionuclide exercise test results in patients with coronary angiograms. J Am Coll Cardiol 1985;6: 1245–1253
Christian TF, Miller T, Bailey KR, Gibbons R. The influence of peak systolic blood pressure on ST-segment depression during exercise in the absence of coronary artery disease. J Am Coll Cardiol 1993;21: 98A
Cooke RA, Ryan P, Chambers JB, Curry PVL. Combined technetium Sesta MIBI perfusion imaging and exercise stress echocardiography in syndrome X: a controlled study. Eur Heart J 1993;14: 287
Kemp HG, Elliot WC, Gorlin R. The angial syndrome with normal coronary arteriography. Trans Assoc Am Physicians 1967;80: 59–70
Greenberg MA, Grose RM, Neuburger N, Silverman R, Strain JE, Cohen MV. Impaired coronary vasodilator responsiveness as a cause of lactate production during pacing-induced ischemia in patients with angina pectoris and normal coronary arteries. J Am Coll Cardiol 1987;9: 743–751
Camici PG, Marraccini P, Lorenzoni R, Buzzigoli G, Pecori N, Perissinotto A, Ferrannini E, UAbbate A, Marzilli M. Coronary hemodynamics and myocardial metabolism in patients with syndrome X: response to pacing stress. J Am Coll Cardiol 1991;177: 1461–1470
Rosen SD, Camici PG. Syndrome X: radionuclide studies of myocardial perfusion in patients with chest pain and normal coronary arteriograms. Eur J Nucl Med 1993;19: 311–314
Borghi A, Di Clemente D, Puddu GM, Ruggeri A, Bugiardini R. Long-term clinical outcome of patients with angina pectoris, normal coronary angiograms and evidence of myocardial ischemia. J Am Coll Cardiol 1993;21: 476A
Rosano GMC, Kaski JC, Collins P, Maseri A, Poole-Wilson PA. Clinical features and long term follow up of 99 consecutive patients with syndrome X. J Am Coll Cardiol 1993;21: 475A
Kemp HG, Kronmal RA, Vlietstra RE, Frye RL, and the Coronary Artery Surgery Study [CASS] participants. Seven year survival of patients with normal or near normal coronary arteriograms. A CASS registry study. J Am Coll Cardiol 1986;7: 479–483
Jones RH, McEwan P, Newman GE, Port S, Rerych SK, Scholz PM, Upton MT, Peter CA, Austin EH, Leong K, Gibbons RJ, Cobb FR, Coleman RE, Sabiston DC. Accuracy of diagnosis of coronary artery disease by radionuclide measurements of left ventricular function during rest and exercise. Circulation 1981;64: 586–601
Gibbons RJ, Lee KL, Cobb F, Jones RH. Ejection fraction response to exercise in patients with chest pain and normal coronary arteriograms. Circulation 1981;64: 952–957
Cannon RO III, Bonow RO, Bacharach SL, Green MV, Rosing DR, Leon MB, Watson RM, Epstein SE. Left ventricular dysfunction in patients with angina pectoris, normal epicardial coronary arteries, and abnormal vasodilator reserve. Circulation 1985;71: 218–226
Favaro L, Caplin JL, Fettiche JJ, Dymond DS. Sex differences in exercise induced left ventricular dysfunction in patients with syndrome X. Br Heart J 1987;57: 232–236
Nihoyannopoulos P, Kaski JC, Crake T, Maseri A. Absence of myocardial dysfunction during stress in patients with syndrome X. J Am Coll Cardiol 1991;18: 1463–1470
Franz IW, Tonnesman U, Erb D. Impaired left ventricular function due to ischemia in hypertensive patients with normal coronary angiogram. J Am Coll Cardiol 1993;21: 287A
Taki J, Nakajima K, Muramori A, Yoshio H, Shimizu M, Hisada K. Left ventricular dysfunction during exercise in patients with angina pectoris and angiographically normal coronary arteries [syndrome X]. Eur J Nucl Med 1994;21: 98–102
Opherk D, Zebe H, Weihe E, Mall G, Durr C, Gravert B, Mehmel HC, Schwarz F, Kubler W. Reduced coronary dilatory capacity and ultrastructural changes of the myocardium in patients with angina pectoris but normal coronary arteriograms. Circulation 1981;63: 817–825
Cannon RO III, Watson RM, Rosing DR, Epstein SE. Angina caused by reduced vasodilator reserve of the small coronary arteries. J Am Coll Cardiol 1983;1: 1359–1373
Cannon RO, Schenke WH, Leon MB, Rosing DR, Urqhart J, Epstein SE. Limited coronary flow reserve after dipyridamole in patients with ergonovine-induced coronary vasoconstriction. Circulation 1987;75: 163–174
Maseri A, Crea F, Kaski JC, Crake T. Mechanisms of angina pectoris in syndrome X. J Am Coll Cardiol 1991;17: 499–506
Tentolouris C, Kyriakides M, Karas S, Tousoulis D, Karakiklas C, Gialafos J, Toutouzas P. Evaluation of coronary flow reserve in patients with mitral valve prolapse, positive exercise test and normal coronary arteries. J Am Coll Cardiol 1993;21: 242A
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Correspondence to: E.H.G. Venneker
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Venneker, E.H.G., van der Wall, E.E. Syndrome X: does it exist?. Eur J Nucl Med 21, 95–97 (1994). https://doi.org/10.1007/BF00175753
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DOI: https://doi.org/10.1007/BF00175753