References
Braestrup C, Schmiechen R, Neff G, Nielsen M, Petersen EN (1982) Interaction of convulsive ligands with benzodiazepine receptors. Science 216:1241–1243
Cowen PJ, Green AR, Nutt DJ, Martin IL (1981) Ethyl β-carboline lowers seizure threshold and antagonizes flurazepam-induced sedation in rats. Nature 290:54–55
Crabbe JC, Young ER, Tam B, Kosobud A, Belknap JK, Laursen SE (1986) Genetic differences in anticonvulsant sensitivity in mouse lines selectively bred for ethanol withdrawal severity. J Pharmacol Exp Ther 239:154–159
File SE, Greenblatt DJ, Martin IL, Brown C (1985) Long-lasting anticonvulsant effects of diazepam in different mouse strains: correlations with brain concentrations and receptor occupancy. Psychopharmacology 86:137–141
Gallaher EJ, Hollister LE, Gionet SE, Crabbe JC (1987) Mouse lines selected for genetic differences in diazepam sensitivity. Psychopharmacology 93:25–30
Little HJ, Nutt DJ, Taylor SC (1984) Acute and chronic effects of the benzodiazepine receptor ligand FG 7142: proconvulsant properties and kindling. Br J Pharmacol 83:951–958
Petersen EN, Jensen LH, Honore T, Braestrup C (1983) Differential pharmacological effects of benzodiazepine inverse agonists. In: Biggio G, Costa E (eds) Benzodiazepine recognition site ligands. Adv Biochem Psychopharmacol 38:57–64
Schweri MM, Paul SM, Skolnick P (1983) Strain differences in susceptibility to the convulsant actions of 3-carbomethoxy-β-carboline. Pharmacol Biochem Behav 19:951–955
Seale TW, Bolger GT, Skolnick P (1985) Inherent differences in convulsant sensitivity to Ro 5–4864, picrotoxinin and pentylenetetrazole among inbred strains of mice. Soc Neurosci Abstr 11:275
Seredenin SB, Blednov YA, Badyshtov BA, Shevchenko NM (1986) Hereditary traits of animals with different reactions to stress and benzodiazepine tranquilizers. In: Valdman AV, (ed) Drug dependence and emotional behavior. Consultants Bureau, New York, pp 49–77
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Nutt, D.J., Lister, R.G. Strain differences in response to a benzodiazepine receptor inverse agonist (FG 7142) in mice. Psychopharmacology 94, 435–436 (1988). https://doi.org/10.1007/BF00174705
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DOI: https://doi.org/10.1007/BF00174705