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Sacrococcygeal teratoma: improved haemostasis after aprotinin?

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Abstract

A neonate underwent resection of an extensive sacrococcygeal teratoma after receiving a bolus of 40,000 Kallikrein Inhibitory Units of aprotinin at induction of anaesthesia. The measured blood loss was 30 ml, less than 10% of blood volume, and was replaced with an intravenous colloid solution, avoiding blood transfusion. The blood loss was low compared to previous resections of similar sacrococcygeal teratomas (mean 118 ml, range 60–250 ml) and suggests that aprotinin may be beneficial in blood conservation during extensive dissections in infants.

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Morecroft, J.A., Lander, A.D., Sury, M.R.J. et al. Sacrococcygeal teratoma: improved haemostasis after aprotinin?. Pediatr Surg Int 8, 366–367 (1993). https://doi.org/10.1007/BF00173370

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