Skip to main content

Advertisement

Log in

Imaging inflammation with human polyclonal immunoglobulin: not looked for but discovered

  • Editorial
  • Published:
European Journal of Nuclear Medicine Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  • Aukland K, Nicolaysen G (1981) Interstitial fluid volume: local regulatory mechanisms. Physiol Rev 61: 556–643

    Google Scholar 

  • Bekerman C, Bitran J (1988) Gallium-67 scanning in the clinical evaluation of human immunodeficiency virus infection: indications and limitations. Semin Nucl Med 18:273–286

    Google Scholar 

  • Bell DR, Watson PD, Renkin EM (1980) Exclusion of plasma proteins in interstitium of tissues from the dog hind paw. Am J Physiol 239: H532-H538

    Google Scholar 

  • Buijs WCAM, Oyen WJG, Claessens RAMJ, Koenders EB, Meeuwis APW, Corstens FHM (1990) Biodistribution and radiation dosimetry of indium-111 labeled immunoglobulin G. Eur J Nucl Med 16:433 (Abstract)

    Google Scholar 

  • Buscombe JR, Lui D, Ensing G, Jong R de, Ell PJ (1990) Tc-99m-human immunoglobulin (HIG)-first results of a new agent for the localization of infection and inflammation. Eur J Nucl Med 16:649–655

    Google Scholar 

  • Buscombe JR, Mille RF, Lui D, Ell PJ (1991) Combined Ga-67 citrate and Tc-99m-human immunoglobulin imaging in human immunodeficiency virus-positive patients with fever of undetermined origin. Nucl Med Commun 12:583–592

    Google Scholar 

  • Calame W, Feitsma HIJ, Ensing GJ, Arndt J-W, Van Furth R, Pauwels EKJ (1991) Binding of 99mTc-labeled polyclonal immunoglobulin to bacteria as a mechanism for scintigraphic detection of infection. Eur J Nucl Med 18:396–400

    Google Scholar 

  • Callery PS, Faith WC, Loberg MD, Fields AT, Harvey EB, Cooper MD (1976) Tissue distribution of technetium-99m and carbon-14 labeled N-(2,6-dimethylphenylcarba-moylmethyl)iminodiacetic acid. J Med Chem 19:962–964

    Google Scholar 

  • Claessens RAMJ, Oyen WIG, Meer JWM van der, Corstens FHM (1990) Scintigraphic detection of inflammation foci with radio-labeled proteins. J Nucl Med 31:810–811 (Abstract)

    Google Scholar 

  • Corstens FHM, Meer JWM van der (1991) Chemotactic peptides: new locomotion for imaging of infection? J Nucl Med 32:491–494

    Google Scholar 

  • Fischman AJ, Rubin RH, Khaw BA, Callahan RJ, Wilkinson R, Keech F, Nedelman F, Dragotakes S, Kramer PB, LaMuraglia, Lind S, Strauss HW (1988) Detection of acute inflammation with 111In-labeled nonspecific polyclonal IgG. Semin Nucl Med 18:335–344

    Google Scholar 

  • Forsgren A (1969) Protein A from Staphylococcus aureus. Production of protein A by bacterial and L forms of S. aureus. Acta Pathol Microbiol Scand 75:481–490

    Google Scholar 

  • ICRP publication 53 (1987a) Radiation dose to the patients from radiopharmaceuticals. Indium-labelled white blood cells (leukocytes). Ann ICRP 18:255–256

    Google Scholar 

  • ICRP publication 53 (1987b) Radiation dose to the patients from radiopharmaceuticals. Technetium-labelled white blood cells (leukocytes). Ann ICRP 18:231–232

    Google Scholar 

  • ICRP publication 53 (1987c) Radiation dose to the patients from radiopharmaceuticals. Gallium citrate. Ann ICRP 18:141–143

    Google Scholar 

  • Juweid M, Strauss HW, Yaoita H, Rubin RH, Fischman AJ (1992) Accumulation of immunoglobulin G at focal sites of inflammation. Eur J Nucl Med 19:159–165

    Google Scholar 

  • Lange JMA, Boucher CAB, Hollak CEM, Wiltink EHH, Reiss P, Van Royen EA, Roos M, Danner SA, Goudsmit J (1990) Failure of zidovudine prophylaxis after accidental exposure to HIV-1. N Engl J Med 322:1375–1377

    Google Scholar 

  • Morrel EM, Tompkins RG, Fischman AJ, Wilkinson RA, Burke F, Rubin RH, Strauss HW, Yarmush ML (1989) Autoradiographic method for quantitation of radiolabeled proteins in tissues using indium-111. J Nucl Med 30:1538–1545

    Google Scholar 

  • Oyen WJG, Claessens RAMJ, Horn JR van, Meer JWM van der, Corstens FHM (1990) Scintigraphic detection of bone and joint infections with indium-111 labeled nonspecific polyclonal human immunoglobulin G. J Nucl Med 31:403–412

    Google Scholar 

  • Oyen WJG, Claessens RAMJ, Meer JWM van der, Corstens FHM (1991) Detection of subacute infectious foci with indium-111 labeled autologous leukocytes and with indium-111 labeled human nonspecific immunoglobulin G: a prospective comparative study. J Nucl Med 32:1854–1860

    Google Scholar 

  • Oyen WJG, Claessens RAMJ, Raemaekers JMM, Pauw BE de, Meer JWM van der, Corstens FHM (1992a) Diagnosing infection in febrile granulocytopenic patients with indium-111 labeled human IgG. J Clin Oncol 10:61–68

    Google Scholar 

  • Oyen WJG, Claessens RAMJ, Meer JWM van der, Corstens FHM (1992b) Biodistribuion and kinetics of radiolabeled proteins in rats with focal infection. J Nucl Med 33: (in press)

  • Pechman T, Tetalman M, Antomatter S, Bekerman C, Olsen J, Chiles J (1978) Diagnostic significance of persistent colonic gallium-67 activity: scintigraphy patterns. Radiology 128:691–695

    Google Scholar 

  • Peters AM, Lavender JP (1991) Imaging inflammation with radio labeled white cells: 99mTc-HMPAO or 111In? Nucl Med Commun 12:923–925

    Google Scholar 

  • Rauh DA (1988) Clinical summary. Phase I study to evaluate the dosimetry and safety of 111In-OB/P # 0001-A-1 [111In-DTPA-immune serum globulin, human (intravenous)] in normal healthy, male volunteers. R.W. Johnson Pharmaceutical Research Institute, Springhouse, Pa

    Google Scholar 

  • Rubin RH, Young LS, Hansen P, Nedelman M, Wilkinson R, Nelles MJ, Callahan R, Khaw BA, Strauss WH (1988) Specific and nonspecific imaging of localized Fisher immunotype 1 Pseudomonas aeruginosa infection with radiolabeled monoclonal antibody. J Nucl Med 29:651–656

    Google Scholar 

  • Rubin RH, Fischmnn AJ, Callahan RJ, Khaw BA, Keeck F, Ahmad M, Wilkinson R, Strauss HW (1989) In-111 labeled nonspecific immunoglobulin scanning in the detection of focal infection. N Engl J Med 321:935–940

    Google Scholar 

  • Saptogino A, Becker W, Wolf F (1990a) 99mTc-labeled polyclonal human immunoglobulin for localization of inflammatory sites-early in vitro results. Nuklearmedizin 29:54–58

    Google Scholar 

  • Saptogino A, Becker W, Wolf F (1990b) Biokinetics and estimation of dose from 99mTc-labeled polyclonal human immunoglobulin (HIG). Nuklearmedizin 30:18–23

    Google Scholar 

  • Sciuk J, Brandau W, Vollet B, Stücker R, Erlemann R, Bartensteins P, Peters PE, Schober O (1991) Comparison of technetium 99m polyclonal human immunoglobulin and technetium 99m monoclonal antibodies for imaging chronic osteomyclitis. Eur J Nucl Med 18:401–407

    Google Scholar 

  • Senda M, Fischman AJ, Weise S, Alpert NM, Correia JA, Rubin RH, Strauss HW (1992) Regional perfusion, oxygen metabolism, blood volume and IgG accumulation at focal sites of infection in rabbits. Eur J Nucl Med 19:166–172

    Google Scholar 

  • Shashoua VE, Holmquist B (1986) Extracellular fluid proteins of goldfish brain: evidence for the presence of proteases and esterases. J Neurochem 47:738–743

    Google Scholar 

  • Spinelli F, Milella M, Sara R, Banfi F, Possa M, Vigorelli R (1990) The value of 99mTc-labeled human immunoglobulin scanning in the evaluation of Crohn's disease. Eur J Nucl Med 16:436

    Google Scholar 

  • Van der Lubbe PAHM, Arndt JW, Calame W, Ferreira TC, Pauwels EKJ, Breedveld FC (1991) Measurement of synovial inflammation in rheumatoid arthritis with technetium 99m labelled human polyclonal immunoglobulin G. Eur J Nucl Med 18:119–123

    Google Scholar 

  • Watson PD, Bell DR, Renkin EM (1980) Early kinetics of large molecule transport between plasma and lymph in dogs. Am J Physiol 239: H525-H531

    Google Scholar 

  • Wegener WA, Velchik MG, Weiss D, Ter S, Byars A, Neptune M, Alavi A (1991) Infectious imaging with indium-111-labeled nonspecific polyclonal human immunoglobulin. J Nucl Med 32:2079–2085

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Corstens, F.H.M., Claessens, R.A.M.J. Imaging inflammation with human polyclonal immunoglobulin: not looked for but discovered. Eur J Nucl Med 19, 155–158 (1992). https://doi.org/10.1007/BF00173274

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00173274

Navigation