Abstract
We compared the pressure-lowering effects of timolol, pindolol, epinephrine and the mixture of timolol and epinephrine with that of placebo over a 12-h period. All agents reduced the pressure significantly but with varying time courses. The mixture of timolol and epinephrine reduced the pressure significantly more than did timolol or epinephrine alone, especially at 12 h after the last administration of the drops.
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Supported in part by Medical Research Council grant MT-1578
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Drance, S.M., Douglas, G.R., Wijsman, K.J. et al. Adrenergic and adrenolytic effects on intraocular pressure. Graefe's Arch Clin Exp Ophthalmol 229, 50–51 (1991). https://doi.org/10.1007/BF00172260
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DOI: https://doi.org/10.1007/BF00172260