Abstract
Phantom studies have demonstrated that factor analysis of medical image sequences using target apex-seeking (FAMIS-TAS) applied to spectral scintigraphic image sequences is an efficient adaptive scatter correction method. We assessed the improvement in quality of clinical images using FAMIS-TAS as compared with two other scatter correction techniques: conventional 20% photopeak window (PW) and scatter window subtraction (SWS). Thirty normal technetium-99m hydroxymethylene diphosphonate bone scans were processed. Bone to soft tissue contrasts and signal-to-noise and contrast-to-noise ratios were measured. The overall image quality was evaluated using an observer testing questionnaire submitted to four physicians. Quantitative parameters showed that FAMIS-TAS images displayed the best bone to soft tissue contrasts and contrast-tonoise ratios, but the lowest signal-to-noise ratios. PW images presented the lowest contrasts and contrast-tonoise ratios, and the highest signal-to-noise ratios. SWS gave intermediate results. According to the observer testing results, PW images showed the lowest bone to soft tissue contrasts and the highest signal-to-noise ratios. FAMIS-TAS images showed the lowest signal-to-noise ratios. The images processed by the three methods displayed the same anatomical information.
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Bonnin, F., Buvat, I., Benali, H. et al. A comparative study of scatter correction methods for scintigraphic images. Eur J Nucl Med 21, 388–393 (1994). https://doi.org/10.1007/BF00171412
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DOI: https://doi.org/10.1007/BF00171412