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Blood flow through irradiated rabbit submandibular glands measured with fluorescein angiography

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Summary

Microvascular injury has been regarded as a contributing factor in irradiation damage of biologic tissues, including morphologic changes and increased permeability of the vascular network. The late irradiation effect on the capillary circulation of salivary glands was studied with dynamic fluorescein angiography. In 31 rabbits one side of the head was exposed to a single radiation dose of 15 Gy. At 4 and 10 months thereafter no significant difference was detectable in the microcirculation between the unshielded and shielded glands.

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References

  1. Cherry CP, Glucksmann A (1959) Injury and repair following irradiation of salivary glands in male rats. Br J Radiol 32: 569–608

    Google Scholar 

  2. Fajardo LF (1982) Salivary glands and pancreas. In: Fajardo LF (ed) Pathology of radiation injury. Masson, New York, pp 77–87

    Google Scholar 

  3. Lund F, Lund S (1973) Dynamic fluorescein angiography. A new method for assessment of skin circulation of the limbs in peripheral arterial disease: In: Shimamoto T, Numano F, Addison GM (eds) Atherogenesis II. Proceedings of the II. International Symposium on Atherogenesis, Thrombogenesis and Pyridinolcarbamate Treatment, Tokyo 1972. Excerpta Med Int Congr Ser 269:333–346

  4. Pratt NE, Sodikoff M (1972) Ultrastructural injury following X-irradiation of rat parotid gland acinar cells. Arch Oral Biol 17:1177–1186

    Google Scholar 

  5. Rubin P, Casarett GW (eds) (1968) Clinical radiation pathology, vol I–II. Saunders, Philadelphia, pp 241–262

    Google Scholar 

  6. Savage NW, Kruger BJ, Adkins KF (1985) Rat submandibular gland microvasculature following fractionated megavoltage irradiation. Austral Dent J 30:2:99–103

    Google Scholar 

  7. Sholley MM, Sodicoff M, Pratt NE (1974) Early radiation injury in rat parotid gland. Lab Invest 31:340–354

    Google Scholar 

  8. Stephens LC, Kian Ang K, Schultheiss TE, King GK, Brock WA, Peters LJ (1986) Target cell and mode of radiation injury in rhesus salivary glands. Radiother Oncol 7:165–174

    Google Scholar 

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Authors and Affiliations

  1. Department of Otolaryngology, Karolinska Hospital, Stockholm, Sweden

    B. H. Ahlner & M. G. Lind

  2. Department of Clinical Physiology, Karolinska Hospital, Stockholm, Sweden

    T. Jogestrand & F. Lund

Authors
  1. B. H. Ahlner
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  2. T. Jogestrand
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  3. M. G. Lind
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  4. F. Lund
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Ahlner, B.H., Jogestrand, T., Lind, M.G. et al. Blood flow through irradiated rabbit submandibular glands measured with fluorescein angiography. Eur Arch Otorhinolaryngol 249, 459–461 (1993). https://doi.org/10.1007/BF00168854

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  • DOI: https://doi.org/10.1007/BF00168854

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