Abstract
In 20 patients with open-angle glaucoma in aphakia or pseudophakia whose intraocular pressure had remained uncontrolled on their current medical therapy, the medication was changed from pilocarpine or carbachol to echothiophate iodide. In all, 12 patients (60%) showed a statistically significant improvement in pressure control, 7 (35%) showed no change, and 1 had higher pressure. One-third of the patients with improved intraocular-pressure control eventually required laser or incisional surgery after a mean of 23 months, whereas the remaining subjects were controlled for the duration of the follow-up, which averaged 26 months. Side effects encountered during echothiophate iodide treatment included ocular irritation, decreased vision, and one retinal detachment.
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References
Alapar JJ (1979) Miotics and retinal detachment. Ann Ophthalmol 11:395–401
Beasley H, Fraunfelder FT (1979) Retinal detachments and topical ocular miotics. Ophthalmology 86:95–98
Harris LS (1971) Dose-response analysis of echothiophate iodide. Arch Ophthalmol 86:502–505
Harris LS (1972) Comparison of pilocarpine and echothiophate iodide in open angle glaucoma. Ann Ophthalmol 4:736–743
Pape LG, Forbes M (1978) Retinal detachment and miotic therapy. Am J Ophthalmol 85:558–566
Reichert RW, Shields MB, Stewart WC (1988) Intraocular pressure response to replacing pilocarpine with carbachol. Am J Ophthalmol 106:747–748
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Reichert, R.W., Shields, M.B. Intraocular pressure response to the replacement of pilocarpine or carbachol with echothiophate. Graefe's Arch Clin Exp Ophthalmol 229, 252–253 (1991). https://doi.org/10.1007/BF00167878
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DOI: https://doi.org/10.1007/BF00167878