Abstract
Since eye pairs are anatomically and pathologically asymmetrical, we attempted to determine whether the transition from ocular hypertension to glaucoma might be typified by lateral differences in either intraocular pressure (IOP), papillary excavation, or visual field. Such lateral differences were sought in a retrospective study of the medical records of 47 patients exhibiting ocular hypertension, of whom 25 remained hypertensives and 22 developed glaucoma during the period considered. Although all visual field indices in the latter group had remained within the normal range, the same side consistently yielded significantly worse results in mean sensitivity, and the absolute value for the lateral difference in these individuals was significantly higher than that found for the patients who did not develop glaucoma. Future glaucoma is manifested when the mean sensitivity remains worse in one eye.
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References
Airaksinen PJ, Alanko HJ (1983) Effect of retinal nerve fibre loss on the optic nerve head configuration in early glaucoma. Graefe's Arch Clin Exp Ophthalmol 220:193–196
Armaly MF (1980) Genetic determination of cup/disc ratio of the optic nerve. Arch Ophthalmol 78:35–43
Arruga J, Sanders MD (1982) Ophthalmologic findings in 70 patients with evidence of retinal embolism. Ophthalmology 89:1336–1347
Ask-Upmark E (1952) On the laterality of cerebral emboli. Acta Med Scand 152:433
Bastian GO (1979) Durchblutungsstörungen des Sehnervs: über die Seitenverteilung und andere dispositionelle Faktoren. Klin Monatsbl Augenheilkd 174:104–108
Cappel DF (1951) Muir's Textbook of Pathology. Arnold, London, p 127
Carel RS, Korczyn AD, Rock M (1985) Ocular tension: comparison between the two eyes. Ophthalmologica 190:98–101
Davanger M (1965) The difference in ocular pressure in the two eyes of the same person. Acta Ophthalmol 43:299–313
Drance SM, Wheeler C, Pattullo M (1968) Uniocular openangle glaucoma. Am J Ophthalmol 65:891–902
Drance SM, Schulzer M, Douglas GR, Sweeney VP (1978) Use of discriminant analysis: II. Identification of persons with glaucomatous visual field defects. Arch Ophthalmol 96:57–73
Etienne R (1982) Unilateral glaucoma. Br J Ophthalmol 56:254–258
Floman NN, Moisseiev J, Blumenthal M (1983) Monocular glaucomatous disc changes following bilateral topical steroid therapy. Glaucoma 5:62–64
Graham PA (1968) The definition of pre-glaucoma. A prospective study. Trans Ophthalmol Soc UK 88:153–165
Hajek J (1969) A course in nonparametric statistics. Freeman, San Francisco, p 52
Hart WM, Yablonksi M, Kass MA, Becker B (1979) Multivariate analysis of the risk of glaucomatous visual field loss. Arch Ophthalmol 97:1455–1458
Hayreh SS (1984) Die Pathogenese des Papillenödems. In: Herzau V (ed) Pathophysiologie des Sehens. (Bücherei des Augenarztes, vol 98). Enke, Stuttgart, pp 55–67
Johnson TD, Zimmermann TJ (1985) A revisit: ocular hypertension, glaucoma suspect, preglaucoma, or glaucoma? Ann Opthalmol 17:390–391
Kass MA, Hart WM, Gordon M, Miller JP (1985) Risk factors favoring the development of glaucomatous visual field loss in ocular hypertension. Surv Ophthalmol 17:456
Kitazawa Y, Horie T, Aoki S, Suzuki M, Nichioda K (1977) Untreated ocular hypertension. Arch Ophthalmol 95:1180–1184
Leydhecker W (1973) Der i.o. Druck bei Gesunden. In: Leydhecker W (ed) Glaukom, 2nd edn. Springer, Berlin Heidelberg New York, p 151
Leydhecker W (1988) Epidemiologie und Risikofaktoren bei Glaukom. Fortschr Ophthalmol 85:38–41
Medici TC, Siegenthaler W (1980) Lungenverschattungen. In: Siegenthaler W (ed) Differentialdiagnose innerer Krankheiten, 14th edn. Thieme, Stuttgart, pp 17–30
Perkins ES (1973) The Bedford glaucoma survey: I. Long-term follow-up of borderline cases. Br J Ophthalmol 57:179–185
Perkins ES (1973) The Bedford glaucoma survey: 11. Rescreening of normal population. Br J Ophthalmol 57:186–192
Peternel P, Veber D, Videcnik V (1979) Carotid arteries in central retinal vessel occlusion as assessed by Doppler ultrasound. Br J Ophthalmol 73:880–883
Ratschow M (1962) Gefäßkrankheiten und Durchblutungsstörungen. In: Ratschow M, Thiel R (eds) Durchblutungsstörungen und das Auge. (Bücherei des Augenarztes, vol 39). Enke, Stuttgart, p 10
Robert Y (1985) Messungen des Rottons der Papille. In: Robert Y (ed) Die klinischen Untersuchungsmethoden der Papille. (Bücherei des Augenarztes, vol 108). Enke, Stuttgart, p 111
Robert Y, Hendrickson P (1984) Color appearance of the papilla in normal and glaucomatous eyes. Arch Ophthalmol 102:1772–1775
Shields MB (1985) A revisit: ocular hypertension, glaucoma suspect, preglaucoma, or glaucoma? Ann Ophthalmol 17:456
Slagsvold JE (1986) The follow-up in patients with pseudoexfoliation of the lens capsule with and without glaucoma. The development of glaucoma in persons with pseudoexfoliation. Acta Ophthalmol 64:241–245
Sponsel WE, Hobley A, Henson DB, Chauhan BC, Dallas NL (1987) Quantitative supra-threshold static perimetry; the value of field score and asymmetry analysis in the early detection of chronic open-angle glaucoma. Doc Ophthalmol Proc Ser 49:217–229
Uhthoff W (1925) Zu den arteriellen und venösen Zirkulationsstörungen der Netzhaut. Ber Dtsch Ophthalmol Ges 25:63
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Thölen, A., Tremmel, L., Maurer, W. et al. Lateral differences indicate future glaucoma. Graefe's Arch Clin Exp Ophthalmol 230, 29–35 (1992). https://doi.org/10.1007/BF00166759
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DOI: https://doi.org/10.1007/BF00166759