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Dosing problems in the use of topical ophthalmic drops

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Abstract

The effect of two drops of the same drug, one instilled immediately after the other, was compared to the effect of a single drop in 100 healthy volunteers. The drugs investigated were tropicamide, 0.125%, and phenylephrine, 2.5%. The mydriatic effect of two drops was 30%–35% stronger than the effect achieved by a single drop.

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Authors and Affiliations

  1. Department of Ophthalmology, Ichilov Hospital, 6 Weitzman Street, 64239, Tel Aviv, Israel

    Anat Loewenstein, Orna Geyer, Anat Blanc & Moshe Lazar

Authors
  1. Anat Loewenstein
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  2. Orna Geyer
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  3. Anat Blanc
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  4. Moshe Lazar
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Correspondence to: A. Loewenstein

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Loewenstein, A., Geyer, O., Blanc, A. et al. Dosing problems in the use of topical ophthalmic drops. Graefe's Arch Clin Exp Ophthalmol 230, 378–379 (1992). https://doi.org/10.1007/BF00165949

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  • DOI: https://doi.org/10.1007/BF00165949

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