Skip to main content
Log in

Deeply invasive squamous cell carcinoma of the conjunctiva: case report

  • Published:
International Ophthalmology Aims and scope Submit manuscript

Abstract

A 82-year-old man had a bulbar exophytic mass protruding through the lids and extending from the nasal side of the limbus to the caruncola in one eye. The lesion appeared 9 months before as a limbal nodule and showed a painless, slow evolution, ultimately leading to enucleation. The histopathologic examination of the neoplasm and eyeball showed an invasive squamous cell carcinoma of the conjunctiva which invaded the deep subepithelial tissue and reached the scieral surface. The evolution and pathologic features of this uncommon neoplasm were similar to that described in other cases previously reported.

Such a clinical course is suggestive also of mucoepidermoid carcinoma of the conjunctiva, which closely resembles squamous cell carcinoma, but is more aggressive and locally invasive. However, after staining for mucin, this diagnosis was ruled out.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Brownstein S. Mucoepidermoid carcinoma of the conjunctiva with intraocular invasion. Ophthalmology 1981; 88: 1226–9.

    Google Scholar 

  2. Fraunfelder FT, Wingfield D. Management of intraepithelial conjunctival tumours and squamous cell carcinoma. Am J Ophthalmol 1983; 95: 359–63.

    Google Scholar 

  3. Gamel JW, Eiferman RA, Guibor P. Mucoepidermoid carcinoma of the conjunctiva. Arch Ophthalmol 1984; 102: 730–1.

    Google Scholar 

  4. Iliff WJ, Marback R, Green WR. Invasive squamous cell carcinoma of the conjunctiva. Arch Ophthalmol 1075; 93: 119–22.

    Google Scholar 

  5. Nicholson DH, Herschler J. Intraocular extension of squamous cell carcinoma of the conjunctiva. Arch Ophthalmol 1977; 95: 843–6.

    Google Scholar 

  6. Rao NA, Font RL. Mucoepidermoid carcinoma of the conjunctiva: A clinicopathologic study of five cases. Cancer 1976; 38:1699–709.

    Google Scholar 

  7. Rasteiro A, Cunha-Vaz JG. Squamous cell carcinoma of the limbus with intraocular invasion. Ophthalmologica 1987; 172: 332–6.

    Google Scholar 

  8. Reese AB. Epithelial Tumors. In: Tumors of the Eye. Paul B. Holber, Inc., 1951.

  9. Searl SS, Krigstein HJ, Albert DM, Grove AS Jr. Invasive squamous cell carcinoma with intraocular mucoepidermoid features. Arch Opthalmol 1982; 100: 109–11.

    Google Scholar 

  10. Wexler SA, Wallow IHL. Squamous cell carcinoma of the conjunctiva presenting with intraocular extension. Arch Ophthalmol 1985; 103: 1175–7.

    Google Scholar 

  11. Yanoff M, Fine BS. Cancerous epithelial lesions. In: Ocular Pathology. Harper and Row, Philadelphia, 1982.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

De Felice, G.P., Viale, G. & Caroli, R. Deeply invasive squamous cell carcinoma of the conjunctiva: case report. Int Ophthalmol 14, 241–244 (1990). https://doi.org/10.1007/BF00159858

Download citation

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00159858

Key words

Navigation