Abstract
We performed a retrospective study on 45 patients admitted to the Rotterdam Eye Hospital and the Ophthalmic Department of the Academic Medical Center in Amsterdam with pseudophakic endophthalmitis. Vitreous loss during cataract extraction was associated with a significantly increased risk of postoperative endophthalmitis when compared with uncomplicated cataract extraction (p < 0.0001). The incidence of pseudophakic endophthalmitis in diabetic patients was not significantly higher as compared to non-diabetic patients. Vitrectomy in the treatment of postoperative endophthalmitis did not improve the final visual acuity, probably because of selection bias. Methiciliin and cephazolin, used intravitreally against gram-positive organisms, failed to provide a good coverage for endophthalmitis due to Staphylococcus epidermidis.
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References
Javitt JC, Vitale S, Canner JK, et al. National outcomes of cataract extraction: Endophthalmitis following inpatient surgery. Arch Ophthalmol 1991; 109: 1085–89.
Kattan HM, Flynn HW, Pflugfelder SC, et al. Nosocomial endophthalmitis survey: Current incidence of infection after intraocular surgery. Ophthalmology 1991; 98: 227–38.
Puliafito CA, Baker AS, Haaf J, et al. Infectious endophthalmitis: Review of 36 cases. Ophthalmology 1982; 89: 921–29.
Forster RK, Abbott RL, Gelender H. Management of infectious endophthalmitis: Ophthalmology 1980; 87: 313–19.
Driebe WT, Mandelbaum S, Forster RK. Pseudophakic endophthalmitis: Diagnosis and management. Ophthalmology 1986; 93: 442–48.
Davis JL, Koidou-Tsiligianni A, Pflugfelder SC, et al. Coagulase-negative staphylococal endophthalmitis: Increase in antimicrobial resistance. Ophthalmology 1988; 95: 1404–10.
Peyman GA, Vastine DW, Raichand M. Symposium: Postoperative endophthalmitis Experimental aspects and their clinical applications. Ophthalmology (AAO) 1978; 85: 374–85.
Talley AR, D'Amico DJ, Talamo JH, et al. The role of vitrectomy in the treatment of postoperative endophthalmitis: An experimental study. Arch Ophthalmol 1987; 105: 1699–702.
Diamond JG. Intraocular management of endophthalmitis: The systemic approach. Arch Ophthalmol 1981; 99: 96–99.
Doft BH. The endophthalmitis vitrectomy study. Arch Ophthalmol 1991; 109: 487–89.
Maylath FR, Leopold IH. Study of experimental intraocular infection, I: The recoverability of organisms inoculated into ocular tissues and fluids. Am J Ophthalmol 1955; 40: 86–101.
Speaker MG, Milch FA, Shah MK, et al. Role of external bacterial flora in the pathogenesis of acute postoperative endophthalmitis. Ophthalmology 1991; 98: 639–50.
Menikoff JA, Speaker MG, Marmor M, et al. A case control study of risk factors for postoperative endophthalmitis. Ophthalmology 1991; 98: 1761–68.
Christy NE, Lall P. Postoperative endophthalmitis following cataract surgery: Effects of subconjunctival antibiotict and other factors. Arch Ophthalmol 1973; 90: 361–66.
Schoenbaum SC. Infection in diabetes. In: Kozak GP, ed. Clinical diabetes mellitus. Philadelphia: WB Saunders, 1982: 327–32.
Allan HF, Mangiaracine AB. Bacterial endophthalmitis after cataract extraction: A study of 22 infections in 20.000 operations. Arch Ophthalmol 1964; 72: 454–62.
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Jager, G.V., Brinkman, C.J.J., Van Tilburg, C.J.G. et al. Pseudophakic endophthalmitis. Doc Ophthalmol 82, 109–114 (1992). https://doi.org/10.1007/BF00157000
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DOI: https://doi.org/10.1007/BF00157000