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The pattern electroretinogram by skin electrodes: Effect of spatial frequency and age

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Abstract

Steady-state (8 Hz) pattern electroretinograms in response to sinusoidal gratings were recorded from 18 elder subjects (mean age 62.7 years) and 22 young subjects (mean age 27 years) by means of skin electrodes. All subjects were free from ocular pathology and their corrected visual acuity was 1.0 or better. In young subjects the second harmonic amplitude as a function of spatial frequency is spatially tuned, with a maximum at around 1.7 c/deg. The response of elder subjects is significantly (P < 0.05) reduced over the whole range of spatial frequency as compared with that of younger ones. This decrease is more marked (P < 0.01) at intermediate spatial frequencies, resulting in a shallower tuning. The response phase is not significantly different between young and elder subjects.

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Porciatti, V., Falsini, B., Scalia, G. et al. The pattern electroretinogram by skin electrodes: Effect of spatial frequency and age. Doc Ophthalmol 70, 117–122 (1988). https://doi.org/10.1007/BF00154742

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