Abstract
The left eye of a 77 year old male patient was enucleated because of absolute glaucoma. This eye showed subnormal electroretinogram (ERG) and oscillatory potentials preoperatively, but the other eye showed Schubert-Bornschein type ERG and monophasic dark adaptation curve. Light and electron microscopic studies of the left eye showed a normal arrangement of discs of rod outer segments, normal synaptic ends of the photoreceptors, and complete loss of ganglion cells. From the subnormal ERG in the left eye we assumed it was originally Schubert-Bornschein type ERG but inverted to subnormal type ERG following the loss of inhibitory mechanisms. Thus we propose that the cause of night blindness in congenital stationary cases with Schubert-Bornschein type ERG may be related to the mechanisms inhibitory to cells of the bipolar layer.
Similar content being viewed by others
References
Ayaki M, Oguchi Y and Matuhashi M (1984) Unilateral night blindness with normal fundus. Am J Ophthalmol 98:630–632
Babel J (1963) Constatations histologiques dans 1' amaurose infantile de Leber et dans diverses formes d' héméralopie. Ophthalmologica 145:399–402
Carr RE, Ripps H, Siegel IM and Weale RA (1966a) Rhodopsin and the electrical activity of the retina in congenital night blindness. Invest Ophthalmol 5:497–507
Carr RE, Ripps H, Siegel IM and Weale RA(1966a) Visual functions in congenital night blindness. Invest Ophthalmol 5:508–514
Gills JP (1966) The electroretinogram after section of the optic nerve in man. Am J Ophthalmol 62:287–291
Heckenlively JR, Martin DA and Rosenbaum AL (1983) Loss of electroretinographic oscillatory potentials, optic atrophy, and dysplasia in congenital stationary night blindness. Am J Ophthalmol 96:526–534
Kelsey JH and Arden GB (1971) Acquired unilateral loss of dark adaptation. Br J Ophthalmol 55:38–43
Lachapelle P, Little JM and Polomeno RC (1983) The photopic electroretinogram in congenital stationary night blindness with myopia. Invest Ophthalmol Vis Sci 24:442–450
Ripps H (1982) Night blindness revisited: from man to molecules. Invest Ophthalmol Vis Sci 23:588–609
Ripps H, Carr RE, Siegel IM and Greenstein VC (1984) Functional abnormalities in vincristine-induced night blindness. Invest Ophthalmol Vis Sci 25:787–794
Suzuki TA (1959) ERG of congenital totally color-weak eye accompanied by lesion of optic nerve. Arch Ophthalmol 62:386–395
Vaghefi HA, Green WR, Kelley JS, Sloan LL, Hoover RE and Patz A (1978) Correlation of clinicopathologic findings in a patient, congenital night blindness, branch vein occlusion, cilioretinal artery, drusen of the optic nerve head, and intraretinal pigment lesion. Arch Ophthalmol 96:2097–2104
Watanabe I, Toyama K, Sano M and Kato E (1980) An electrophysiological and psychophysical study in patients with congenital stationary night blindness. Folia Ophthalmol Jpn 31:799–802
Witzel DA, Smith EL, Wilson RD and Aguirre GD (1978) Congenital stationary night blindness in an animal model. Invest Ophthalmol Vis Sci 17:788–795
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Watanabe, I., Taniguchi, Y., Morioka, K. et al. Congenital stationary night blindness with myopia: a clinicopathologic study. Doc Ophthalmol 63, 55–62 (1986). https://doi.org/10.1007/BF00153012
Issue Date:
DOI: https://doi.org/10.1007/BF00153012