Abstract
Similarities between serological alterations and retinal degeneration occurring in natural and experimental CJD and in some forms of human retinal degeneration have recently been reported. In the present paper a family from an areal focal accumulation of CJD in Central Slovakia with 1 histopathologically verified case of Creutzfeldt-Jakob disease and 2 case of retinitis pigmentosa is described. Neuropathological and epidemiological data obtained in investigated patients are discussed from the point of view of a possible relationship between the slow virus infections caused by unconventional agents and degenerative disease affecting the ocular system.
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Mitrova', E. A case of Creutzfeldt-Jakob disease related to familial retinitis pigmentosa patients. Eur J Epidemiol 4, 55–59 (1988). https://doi.org/10.1007/BF00152693
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DOI: https://doi.org/10.1007/BF00152693