Abstract
A patient with a malignant cerebral mixed oligodendroglioma-astrocytoma presented with a severe, painful S-1 radiculopathy. Neuroradiological examinations revealed an extradural soft-tissue mass compressing the first sacral nerve root. Spinal fluid examination and myelography gave no evidence of intradural disease. Surgery confirmed the presence of metastatic glioma compressing the S-1 nerve root. The tumor was entirely epidural in location. Mechanisms of dissemination are discussed.
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Russell, DS, Rubinstein, LJ: Pathology of Tumors of the Nervous System. Williams and Wilkins Co., Baltimore, 1977, pp 331–347.
Glasauer, FE, Yuan, RHP: Intracranial tumors with extracranial metastasis: Case report and review of literature. J Neurosurg 20:474–493, 1963.
Liwnicz, TM, Rubenstein, LJ: Pathways of extraneural spread in metastasizing gliomas: A report of three cases and critical review of the literature. Hum Path 10:453–467, 1979.
Duffy, PE, Graf, L, Rapport, MM: Identification of glial fibrillary acidic protein by the immunoperoxidase method in human brain tumors. J Neuropath Exp Neuro 36:545 - 652, 1977.
Cairns, M, Russell, DS: Intracranial and spinal metastases in gliomas of the brain. Brain 57:377–420, 1931.
Polmeteer, FE, Kernohan, JW: Meningeal gliomatosis — A study of 42 cases. Arch Neuro Psych 57:593–616, 1947.
Yung, WA, Horten, BC, Shapiro, WR: Meningeal gliomatosis: A review of 12 cases. Ann Neuro 8:605–608, 1980.
Wood, EM, Taveras, JM, Pool, JL: Myelographic demonstration of spinal cord metastases from primary brain tumors. Am J Roentgenol 69:221–230, 1953.
Bryan, P: CSF seeding of intracranial tumors: A study of 96 cases. Clin Radiol 25:255 - 360, 1974.
Ley, A, Campillo, D, Oliveras, C: Extracranial metastases of glioblastoma multiforme. J Neurosurg 18:313 - 330, 1961.
Smith, DR, Hardman, JM, Earle, KM: Metastasizing tumors of the central nervous system. J Neurosurg 31:50–58, 1969.
Komatsu, K, Hiratsuka, H, Takahashi, S, Kamisasa, A, Inaba I: Widespread extracranial metastases of glioblastoma multiforme — Report of case and clinical pathological review of cases in the literature. Bull Tokyo Med Dent Univ 19:29 - 49, 1972.
Wakamatsu, T, Matsuo, T, Kawano, S, Teramoto, S, Matsumura H: Extracranial metastasis of intracranial tumor —Review of literature and report of a case. Acta Pathol Jpn 22:166 - 169, 1972.
Pasquier, B, Pasquier, D, Golet, AN, Panh, MH, Couderc, P: Extraneural metastases of astrocytomas and glioblastomas — Clinical pathological study of two cases and review of literature. Cancer 45:112–125, 1950.
Henson, RA, Urich, H: Cancer and the nervous system. The neurological manifestationis of systemic malignant disease. Blackwell Scientific Publications, Oxford, 1982, pp 155 - 160.
Willis, RA: The spread of tumours in the human body, 3rd Ed. Butterworth, London, 1982, p 235.
Chason, JL, Walker, FB, Landers, JW: Metastatic carcinoma in the central nervous system and dorsal root ganglia — A prospective autopsy study. Cancer 16:781- 787, 1963.
Johnson, PC: Hematogenous metastases of carcinoma to dorsal root ganglia. Acta Neuropathol (Berl) 38:171 -172, 1977.
Johnson, PC: Fenestrated endothelium in the human peripheral nervous system. J Neuropath Exp Neurol 36:607, 1977.
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Matsumotol, J.Y., O'Neilll, B.P., Piepgras, D.G. et al. Metastatic malignant glioma with resultant extradural compression of a sacral nerve root. J Neuro-Oncol 4, 227–231 (1987). https://doi.org/10.1007/BF00150614
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DOI: https://doi.org/10.1007/BF00150614