Abstract
We report a group of 13 cases of Creutzfeldt-Jakob disease treated in the region of Parma (Italy) between 1975 and 1984.
An extensive study did not point to any common source of infection.
The clinical stereotypy and distinctive neuropathology in this temporo-spatially confined group of patients might be stressed, but the possibility of infection by a single strain of the CJD agent remains speculative.
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References
ArayaG., GalvezS. and CartierL. (1983): A spatiotemporal clustering of Creutzfeldt-Jakob disease in Chile. - Rev. Chil. Neuropsiq. 21:291–295.
BernoulliC., SiefgriedJ. and BaumgartnerG. (1977): Danger of accidental person-to-person transmission of Creutzfeldt-Jakob disease by surgery. - Lancet 1:8009: 478–479.
BrownP. (1980): An epidemiologic critique of Creutzfeldt-Jakob disese. - Epidem. Rev. 2: 113–135.
BrownP., Rodgers-JohnsonP., CathalaFr., GibbsC.J. and GajdusekD.C. (1984): Creutzfeldt-Jakob disease of long duration: Clinicopathological characteristics, transmissibility, and differential diagnosis. - Ann. Neurol. 16: 295–304.
BrownP., GajdusekD.C., GibbsC.J. and AsherD.M. (1985): Potential epidemic of Creutzfeldt-Jakob disease from human growth hormone. - N. Engl. J. Med. 313: 728–731.
ChatelainJ., CathalaFr., BrownP., RaharisonS. and GajdusekD.C. (1981): Epidemiologic comparison between Creutzfeldt-Jakob disease and scrapie in France during the 12-years period 1968–1979. - J. Neurol. Sci. 51: 329–337.
DuffyP., WolfJ., CollinsG., DeVoeA.G.StreetenB. and CowenD. (1974): Possible person-to-person transmission of Creutzfeldt-Jakob disease - N. Engl. J. Med. 290: 692–693.
FoncinJ.F., GachesJ., CathalaFr., Ali SherifE. and LeBeauJ. (1980): Transmission jatrogéne interhumaine possible de la maladie Creutzfeldt-Jakob avec atteinte des grains du cervelet. - Rev. Neurol. 136: 279–280.
HaltiaM., KovanenJ., VanCrevelH., BotsTh. A.M. and StefankoS. (1979): Familial Creutzfeldt-Jakob disease. - J. Neurol. Sci. 42: 381–389.
Harries-JonesR., KnightR., WillR.G., CousensS., SmithP.G. and MattehwsW.B. (1988): Creutzfeldt-Jakob disease in England and Wales, 1980–1984: a case control study of potential risk factors. - J. Neurol. Neurosurg. Psychiat. 51: 1113–1119.
JellingerK., SeitelbergerF., HeissW.D. and BolczabekW. (1972): Koniugale Form der subakuten spongiosen Enzephalopathie (Jakob-Creutzfeldt Erkrankung). - Wien. Min. Wochenschr. 84:245–249.
JonesD.P. and NevinS. (1954): Rapidly progressive cerebral degeneration (subacute vascular encephalopathy) with mental disorders, focal disturbances, and myoclonic epilepsy. - J. Neurol. Neurosurg. Psych. 17: 148–159.
KahanaE., AlterM. and BrahamG. (1974): Creutzfeldt-Jakob disease: focus among Libyan Jews in Israel. - Science, 183: 90–91.
KovanenJ. and HaltiaM. (1988): Descriptive epidemiology of Creutzfeldt-Jakob disease in Finland. - Acta Neurol. Scand. 77: 474–480.
LechiA., TedeschiF., ManciaD., PietriniV., TagliaviniF., TerzanoM.G. and TrabattoniG. (1983): Creutzfeldt-Jakob disease: clinical, EEG and neuropathological findings in a cluster of eleven patients. - It. J. Neurol. Sci 1: 47–59.
MarshR.F., BurgerD., EckroadeR.J., Zu RheinG.M. and HansonR.P. (1969): A preliminary report on the experimental host range of the transmissible mink encephalopathy. - J. Infect. Dis. 120: 713–719, 72.
MayW.W. (1968): Creutzfeldt-Jakobdisease. I: Survey of the literature and clinical diagnosis. Acta Neurol. Scand. 44: 1–32.
MayerY., OrolinD. and MitrovaE. (1977): Cluster of Creutzfeldt-Jakob disease and presenile dementia. -Lancet 2: 8031–256.
Majtényi C. (1975): The familial occurrence of Jakob-Creutzfeld disease. Proc. 7th Int. Congr. Neuropathol., Budapest 1–7 sept. 1974. Exc. Med, Series N. 362 (75–78), Amsterdam.
MatthewsW.B. (1975): Epidemiology of Creutzfeldt-Jakob disease in England and Wales. - J. Neurol. Neurosurg. Psych. 38: 210–213.
PrichardJ., ThadaniY., KalbR., ManuelidisE. and HadlerJ. (1987): Rapidly progressive dementia in a patient who received a cadaveric dura mater graft. -J.A.M.A. 257: 1036–1037.
WillR.G. and MatthewsW.B. (1982): Evidence for case-to case transmission of Creutzfeldt-Jakob disease. - J. Neurol. Neurosurg. Psych. 45: 235–238.
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Trabattoni, G., Lechi, A., Bettoni, L. et al. Considerations on a group of 13 patients with Creutzfeldt-Jakob disease in the region of Parma (Italy). Eur J Epidemiol 6, 239–243 (1990). https://doi.org/10.1007/BF00150425
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DOI: https://doi.org/10.1007/BF00150425