Abstract
Between September, 1988 and January, 1989 a common source outbreak of 47 cases of serologically confirmed hepatitis A occurred in a town of central Italy. Thirty-eight cases were primary, three co-primary and six secondary. The highest age-specific attack rate was seen in subjects aged 15–24 years (120 per 100,000); the mean age of cases was 24.6 years and the median age was 22 years. A matched triplet case-control study showed significant association between the disease and consumption of either raw mussels (41% of cases, compared with 10% of controls; P < 0.0001) or a single brand of mineral water (63% of cases, compared with 41% of controls; P < 0.05). The mean age of the cases reflects the shift in primary susceptibility to the infection from younger to older age groups, a finding which has recently been demonstrated by several seroepidemiological surveys in Italy.
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References
BenensonM.W., Taka FujiE. T, Bancroft W.H. et al. (1980): A military community outbreak of hepatitis type A related to transmission in a child care facility.- Am. J. Epidemiol. 112: 471–481.
D'ArgenioP., EspositoD., MeleA., RapicettaM., StroffoliniT. and PasquiniP. (1989): Decline in the exposure to hepatitis A and B infections in children in Naples, Italy. - Public Health. 103: 385–389.
DenesA.E., SmithL., Hindman S.H. et al. (1977): Foodborne hepatitis A infection: a report of two urban restaurants associated outbreak. - Am. J. Epidemiol. 105: 156–162.
GrecoD., DeGiacomiG., Piersante G.P. et al. (1986): A person to person hepatitis A outbreak. - Int. J. Epidemiol. 15: 108–111.
LathoonR.H. and SchableC.A. (1982): Foodborne hepatitis A at a family reunion. - Am. J. Epidemiol. 115: 640–645.
MerlettiL. and FrongilloR.F. (1980): Incidenza di anticorpi anti-HAV nella popolazione sana Umbra. -Ann. Sclavo, 22: 165–168.
NoahN.D. (1981): Foodborne outbreak of hepatitis A.- Med. Lab. Sci. 38: 428.
O'MahonyM.C., GoochCD., SmythD.A., ThrussellA.J., BartlettC.L.R. and NoahN.D. (1983): Epidemic hepatitis A from cockles. - Lancet, i: 518–520.
RosembergM.L., KoplanF.P. and PollardR.A. (1980): The risk of acquiring hepatitis from sewage-contaminated water. - Am. J. Epidemiol. 112: 17–22.
RothmanK.J. and BoiceJ.D. (1982): Epidemiologic analysis with a programmable calculator 2nd Edition. Epidemiology Resource Inc., Boston.
Stroffolini T., Franco E., Romano G. et al. (1989): Hepatitis A virus infection in children in Sardinia, Italy. Community Medicine. (In press).
Stroffolini T., Giammanco A., De Crescenzo L. et al. (1989): Changing pattern of hepatitis A virus infection in children in Palermo, Italy. - Eur. J. Epidemiol. (In press).
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Stroffolini, T., Biagini, W., Lorenzoni, L. et al. An outbreak of hepatitis a in young adults in central Italy. Eur J Epidemiol 6, 156–159 (1990). https://doi.org/10.1007/BF00145788
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DOI: https://doi.org/10.1007/BF00145788