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LP(A): A link between thrombosis and atherosclerosis

European Journal of Epidemiology volume 8, pages 76–78 (1992)Cite this article

Abstract

Lipoprotein(a), or Lp(a), is a lipoprotein having lipid composition similar to that of LDL, but a protein moiety consisting of ApoB 100 linked by disulfide bridge to apo(a), a glycoprotein with structural similarity to plasminogen. Lp(a) can be both atherogenic and thrombogenic. These two actions are likely to be mutually operative, a fact that on a molar basis makes Lp(a) more of a cardiovascular pathogen than LDL.

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Affiliations

  1. Department of Medicine - Biochemistry and Molecular Biology, University of Chicago, 5841 South Maryland Avenue, Box 231, 60637, Chicago, Illinois, USA

    A. M. Scanu

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  1. A. M. Scanu
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Scanu, A.M. LP(A): A link between thrombosis and atherosclerosis. Eur J Epidemiol 8, 76–78 (1992). https://doi.org/10.1007/BF00145354

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  • DOI: https://doi.org/10.1007/BF00145354

Key words

  • Atherosclerosis
  • Lp(a)
  • Thrombosis