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Factor VIII and coronary heart disease

  • Haemostatic function and cardiovascular disease
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Abstract

In plasma, Factor VIII is bound to its carrier protein, von Willebrand Factor (vWF). Therefore, the levels of these two factors vary together. From studies in the general population, in patients with coronary heart disease and in hemophilia patients, an association between Factor VIII levels and coronary heart disease clearly emerges.

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Authors and Affiliations

  1. Department of Clinical Epidemiology, Leiden University Hospital, Bld 1 CO-P, P.O. Box 9600, 2300, Leiden, RC, The Netherlands

    F. R. Rosendaal

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  1. F. R. Rosendaal
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Rosendaal, F.R. Factor VIII and coronary heart disease. Eur J Epidemiol 8 (Suppl 1), 71–75 (1992). https://doi.org/10.1007/BF00145353

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