Summary
Using a pulsed gas and liquid flow and with cells directly adsorbed on to a suitably-formed support, aerobic transformations can be carried out in a fixed-cell reactor with significant gain in efficiency. Immobilized cells of Acetobacter on cordierite can produce acetic acid at a high rate which, at different dilution rates, may be limited either by product inhibition or by oxygen transfer requirements.
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Ghommidh, C., Navarro, J.M. & Durand, G. Acetic acid production by immobilized acetobacter cells. Biotechnol Lett 3, 93–98 (1981). https://doi.org/10.1007/BF00145117
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DOI: https://doi.org/10.1007/BF00145117