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Ovine scrapie: Follow-up of sheep belonging to an endemic scrapie-infected flock

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Abstract

There is a close similarity between the unconventional virus-induced ovine scrapie and human Creutzfeldt-Jakob disease. Since infection might be transmitted orally, the ovine production of an endemically scrapie-infected farm was studied. About 80% of the annual production are sold (50% as butcher-meat, 30% as breeding animals), and scrapie appears in 20% of the sheep kept on the farm. Was the same proportion of butcher-meat animals scrapie-infected? Since the scrapie agent has been detected in “clinically normal” lambs, the same problem occurs with breeding-sheep and “apparently healthy” animals: are they carriers of the pathogenic agent? Are they responsible for the spread of the ovine disease and/or of the human disease?

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Authors and Affiliations

  1. Formation de Recherche Associée C. Bernard “Neurochilnie des Communications Cellulaires”, Hôpital St Louis, 1 Avenue C. Vellefaux, 75475, 10, Paris Cedex, France

    J. Chatelain

  2. Laboratoire de Biologie Cellulaire et d Immunologie, Faculté de Mécine, Avenue Kennedy, 30000, Nimes, France

    C. Dautheville-guibal

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  1. J. Chatelain
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  2. C. Dautheville-guibal
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Chatelain, J., Dautheville-guibal, C. Ovine scrapie: Follow-up of sheep belonging to an endemic scrapie-infected flock. Eur J Epidemiol 5, 113–116 (1989). https://doi.org/10.1007/BF00145057

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