Skip to main content
SpringerLink
Log in

Silicone-stimulated anthraquinone production and release by Morinda citrifolia in a two-liquid-phase system

  • Published:
Biotechnology Letters Aims and scope Submit manuscript

Summary

A 2.5-fold increase in the release of intracellular anthraquinones was obtained by adding 1 ml L-1 silicone A to suspension cultures of Morinda citrifolia. Cell growth and secondary metabolite production were not affected even at high silicone A concentrations. Performance of the silicone treatment in a two-liquid-phase system (5 ml n-hexadecane/50 ml medium) resulted in a 150% increase of the overall secondary metabolite productivity.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  • Allan, E. (1991). Plant cell culture. In: Plant cell and tissue culture, A. Stafford and G. Warren eds. pp. 1–23, Buckingham: Open University Press.

    Google Scholar 

  • Bassetti, L. and Tramper, J. (1995). Enzyme Microb. Technol. 17, 353–358.

    Google Scholar 

  • Bassetti, L., Hagendoorn, M. and Tramper, J. (1995). J. Biotechnol. 39, 149–155.

    Google Scholar 

  • Buitelaar, R.M. and Tramper, J. (1992). J. Biotechnol. 23, 111–141.

    Google Scholar 

  • Felix, H. (1982). Anal. Biochem. 120, 211–234.

    Google Scholar 

  • Gamborg, O.L., Miller, R.A. and Ojima, K. (1968). Exp. Cell Res. 50, 151–158.

    Google Scholar 

  • Gulik, van, W.M., Meijer, J.J., ten Hoopen, H.J.G., Luyben, K.Ch.A.M. and Libbenga, K.R. (1989). Appl. Microbiol. Biotechnol. 30, 270–275.

    Google Scholar 

  • Kim, D.J. and Chang, H.N. (1990). Biotechnol. Lett. 6, 443–446.

    Google Scholar 

  • King, A.T., Davey, M.R., Mellor, I.R., Mulligan, B.J. and Lowe, K.C. (1991). Enzyme Microb. Technol. 13, 148–153.

    Google Scholar 

  • Lowe, K.C., Davey, M.R., Brian-Power, J. and Mulligan, B.J. (1993). Agro-Food-Industry Hi-Tech. 1, 9–13.

    Google Scholar 

  • Murhammer, D.W. and Goochee, C.F. (1988). Bio/Technol. 6, 1411–1418.

    Google Scholar 

  • Robins, R.J., Payne, J. and Rhodes, M.J.C. (1986). Phytochem., 25, 2327–2334.

    Google Scholar 

  • Zenk, M.H., El-Shagi, H. and Schulte, U. (1975). Planta Medica Suppl. 79–101.

  • Zhong, J.J., Seki, T., Kinoshita, S.I. and Yoshida, T. (1992). World J. Microb. Biotechnol. 8, 106–109.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Food and Bioprocess Engineering Group, Wageningen Agricultural University, P.O. Box 8129, 6700, Wageningen, EV, The Netherlands

    Lucilla Bassetti, Joli Pijnenburg & Johannes Tramper

Authors
  1. Lucilla Bassetti
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Joli Pijnenburg
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Johannes Tramper
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Bassetti, L., Pijnenburg, J. & Tramper, J. Silicone-stimulated anthraquinone production and release by Morinda citrifolia in a two-liquid-phase system. Biotechnol Lett 18, 377–382 (1996). https://doi.org/10.1007/BF00143455

Download citation

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00143455

Keywords

Search

Navigation